'Antibiotic Apocalypse' as Livestock Is Force-Fed 80% of Prescribed Antibiotics Worldwide
By Sophie Linden
A recent report from the World Health Organization (WHO) describes the dangers humanity faces from overprescription of critical infection-fighting drugs, which has led to both superbugs and antibiotics' dwindling efficacy, making humans vulnerable to infections doctors otherwise regarded as benign. While overprescription in humans is a viable issue, recent statements from WHO express heightened concern over the ramifications from their misuse in the meat industry.
Stop Using Antibiotics in Healthy Animals to Prevent the Spread of Antibiotic Resistance is the title of WHO's latest press release, reiterating a message that has been clear for decades. The current culture of force-feeding antibiotics to livestock presents a danger to millions of humans. At present, animals used for livestock are fed around 80 percent of prescribed antibiotics worldwide. The measure has been perpetuated by the low cost of the medicines, as well as antibiotics' proven ability to accelerate growth and weight gain in livestock, effectively speeding up the process of food production. In 2015, the U.S. used 34.3 million pounds of antibiotics on animals. The result is antibiotic-resistant bacteria in animals and humans through food and airborne pathogens.
At present, 700,000 people die each year from antibiotic-resistant infections, and it is predicted that this number could increase to 10 million by 2050, making low-risk operations like hip replacements and treatable urinary tract infections a new health crisis. The Guardian called the collapse an "antibiotic apocalypse," wherein the world is set to face the same surgical risks it did before 1928, when penicillin was discovered. Essentially a century's worth of medical advances could be reversed.
As Tedros Adhanom Ghebreyesus, director-general of WHO, confirmed, "A lack of effective antibiotics is as serious a security threat as a sudden and deadly disease outbreak." This is due in part to a lack of replacement therapies. In its statement, WHO warns that "there are very few promising options in the research pipeline." The Guardian pointed out that this is precipitated by the "failure of pharmaceutical companies to investigate and develop new sources of general medicines for the future." Perhaps, because what's broken is still paying off.
The threat of antibiotic overprescription has been clear since the 1960s, according to Tom Philpott, co-author of Big Chicken: The Incredible Story of How Antibiotics Created Modern Agriculture and Changed the Way the World Eats. But it wasn't until this past January that the U.S. Food and Drug Administration (FDA) made any kind of regulatory change to address the escalating crisis, asking that the livestock industry no longer use antibiotics to accelerate the growth of animals. However, the language used by the FDA has left an opening for the agriculture industry to continue its use of antibiotic treatments, allowing them to be prescribed and used as preventative medicine—treating antibiotics as prophylactics, with plenty of room for indiscretion.
While it is a highly regarded resource, WHO is not a regulatory body, and any reform must happen at the level of government. The troubling lack of concern from the federal government leaves little hope that there will be any change to FDA standards. Given the situation, vegan diets may be one of the main ways to resist the increasing use of antibiotics in livestock, protecting both animal rights and our own immunity to pathogens.
Reposted with permission from our media associate AlterNet.
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Where Does the Deficiency Begin?<p>Nobody knows exactly how much vitamin D a person actually needs. The question of when a deficiency starts is correspondingly controversial. However, vitamin D is becoming increasingly popular.Not only is the pseudo-scientific literature on the "sun vitamin" experiencing an upswing, but the number of published studies has also increased enormously in recent years. For example, in 2019 <a href="https://academic.oup.com/edrv/article/40/4/1109/5126915" target="_blank">a study found that</a> Vitamin D is responsible for keeping the skeleton functional and is associated with cardiovascular diseases, type 2 diabetes and various types of cancer. <br></p>
An All-Rounder<p>Vitamin D levels in the body rise and fall according to sun exposure. If sufficient UV rays reach the skin, the body is able to produce the vitamin itself. However, the human body only derives an estimated 10 to 20 percent of its daily requirement from food.</p><p>The vitamin D that we synthesize from sunlight or food is not biologically active at first. Before the kidneys can produce the biologically active form of the vitamin, known as calcitriol, and release it into the blood, some metabolic processes must take place beforehand.</p><p>In addition, many organs have receptors to which the precursor of calcitriol binds. Further, this substance is also present in blood.</p><p>From this precursor, the organs then produce calcitriol themselves, which the body then uses for countless other processes in the body. This form of vitamin D thus regulates insulin secretion, inhibits tumor growth, and promotes the formation of red blood cells as well as the survival and activity of macrophages, which are important for the <a href="https://www.mdpi.com/2072-6643/5/7/2502/htm" target="_blank">immune system.</a></p>
Low Vitamin D, Severe COVID-19 Disease?<p>A research study carried out <a href="https://www.sciencedirect.com/science/article/pii/S2352364620300067?via%3Dihub" target="_blank">at the University of Hohenheim</a> has now established a link between vitamin D deficiency, certain previous diseases, and severe cases of COVID-19.</p><p>According to the study, "there is a lot of evidence that several non-communicable diseases (high blood pressure, diabetes, cardiovascular diseases, metabolic syndrome) are associated with low vitamin D plasma levels. These comorbidities, together with the often accompanying vitamin D deficiency, increase the risk of severe COVID-19 events."</p><p>"This statement is completely correct," said Martin Fassnacht, head of endocrinology at the University Hospital of Würzburg. However, he qualifies that it is a pure association, "i.e. a mere observation that these events occur together.</p><p>Dr. Fassnacht is very critical of the hype surrounding vitamin D, but not because he denies the vitamin serves important functions. However, studies on humans have not been able to show that vitamin D has the healing powers many often propagate.</p><p>Fassnacht says, "If you take a closer look, the hopes that the administration of vitamin D has a healing effect have not been confirmed so far."</p>
Association Versus Intervention Studies<p>Many studies on the vitamin are association or observational studies. "By definition, these studies cannot prove the causal relationship, but only point to mere correlations," said Fassnacht. The physician tries to illustrate this with an example:</p><p>"Imagine two groups of 80-year-olds. One group is spry, active and does sports. If you compare them with another group living in nursing homes, the difference in vitamin D levels will be dramatic. Life expectancy would also be extremely different."</p><p>But to try to explain the difference in fitness by vitamin D status alone is far too simplistic. "Vitamin D levels are a good measure of how sick someone is. But not more," says Fassnacht. </p><p>According to Fassnacht, none of the intervention studies carried out to date -- that specifically examined the effect of vitamin D on various diseases -- has been able to confirm the previous association and laboratory studies or the presumed positive effect of vitamin D.</p>
Further Research Is Needed<p>"If a coronavirus infection is suspected, it is therefore absolutely necessary to check the vitamin D status and quickly correct any possible deficit," said the recommendation of the paper published by the University of Hohenheim.</p><p>"Studies are underway to see whether vitamin D helps in COVID-19 infection, but I personally do not believe that this is really the case," says endocrinologist Fassnacht. Nevertheless, he says it is of course useful to carry out these studies.<br></p><p>"I don't want to rule out that there are actually subgroups of people who benefit from an additional vitamin D dose," he says. After all, this has been proven to be the case with a severe deficit.</p><p>In view of the study situation, Fassnacht does not think much of preventive, nationwide vitamin D substitutes. "My belief that the vitamin helps somewhere is very low. But, of course, I can be wrong."</p>
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