42 Nobel Laureates Urge Trudeau to Act With 'Moral Clarity' and Stop Climate-Wrecking Teck Frontier Mine
By Jessica Corbett
In an open letter to Canadian Prime Minister Justin Trudeau and Deputy Prime Minister Chrystia Freeland, 42 Nobel laureates implored the federal government to "act with the moral clarity required" to tackle the global climate crisis and stop Teck Resources' proposed Frontier tar sands mine.
"The importance of leadership in the coming few years cannot be understated," reads the letter, published Friday in the Guardian's opinion section. "Governments are lagging scandalously behind what science demands, and what a growing and powerful people-powered movement knows is necessary."
"There is enough carbon embedded in already operating oil, gas, and coalfields and mines to take us beyond 2°C, let alone 1.5°C," the letter continues, referencing key temperature targets of the 2015 Paris climate accord. "The implications of this are clear: there is no room for expansion of the fossil fuel sector. There is no room for the Teck Frontier tar sands mine."
According to the letter:
Projects that enable fossil fuel growth at this moment in time are an affront to our state of climate emergency, and the mere fact that they warrant debate in Canada should be seen as a disgrace. They are wholly incompatible with your government's recent commitment to net-zero greenhouse gas emissions by 2050. And with clear infringements on First Nations rights, such projects fly in the face of rhetoric and purported efforts towards reconciliation.
The response to the climate crisis will define and destroy legacies in the coming years, and the qualifications for being on the right side of history are clear: an immediate end to fossil fuel financing and expansion along with an ambitious and just transition away from oil and gas production towards zero carbon well before mid-century.
Signatories to the letter are from all around the world and have received Nobel prizes in chemistry, economics, literature, medicine, peace, and physics dating back to 1973. They include Canadian author Alice Munro, awarded a literature prize in 2013, and Canadian biologist Jack W. Szostak, awarded a medicine prize in 2009.
The tar sands project, first proposed in 2011, has pitted environmentalists in Canada and across the globe against conservatives in Alberta, where the mine could create thousands of jobs while producing about 260,000 barrels of oil daily and four million tons of climate-heating emissions annually. Trudeau's cabinet is expected to weigh in sometime this month.
"Teck still hasn't committed to building Frontier if it's approved," Bloomberg reported last week. "The Vancouver-based company's current focus is on advancing the project through the regulatory process, and further decisions will depend on the outcome of that process, market conditions, and other considerations, said Chris Stannell, a Teck spokesman."
Although Trudeau often presents himself as committed to addressing the climate crisis, the Liberal prime minister and his government have been criticized for decisions that conflict with scientists' warnings that the world must rapidly move to 100 percent renewable energy to avert climate catastrophe. One such decision was the Trudeau government buying the Trans Mountain pipeline and long-delayed expansion project in 2018, which Indigenous people and climate activists continue to challenge in court.
Among those opposed to the Frontier mine are leaders and members of Extinction Rebellion, Indigenous Climate Action, the Tiny House Warriors and the Union of British Columbia Indian Chiefs, who have held protests aimed at pressuring the Canadian government to block the contested project.
"Ultimately, this mine will be so devastating to the climate, and we're in a climate crisis," Extinction Rebellion member Sarah Flynn told CBC News in January, "so the short-term advantages of the jobs and the income that this mine will offer will be far outweighed by the climate devastation that the whole world will experience."
Grand Chief Stewart Phillip of the Union of BC Indian Chiefs told the Toronto Star last month that Trudeau should "walk the walk" of transitioning to a green economy. Phillip noted that "there were commitments made during the last election that the Trudeau government would make decisive moves toward renewable energy and this is an opportunity to follow through on those promises."
In an op-ed for the Guardian earlier this month, author and activist Bill McKibben wrote that "it's disturbing in a different way to watch leaders pretend to care — a kind of gaslighting that can reduce you to numb nihilism. Trudeau, for all his charms, doesn't get to have it both ways: if you can't bring yourself to stop a brand-new tar sands mine then you're not a climate leader."
Reposted with permission from Common Dreams.
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By Jacob L. Steenwyk and Antonis Rokas
From the mythical minotaur to the mule, creatures created from merging two or more distinct organisms – hybrids – have played defining roles in human history and culture. However, not all hybrids are as fantastic as the minotaur or as dependable as the mule; in fact, some of them cause human diseases.
When Looking Through a Microscope Isn’t Close Enough.<p>For the last few years, <a href="http://www.rokaslab.org/" target="_blank">our team at Vanderbilt University</a>, <a href="https://www.researchgate.net/lab/Gustavo-Goldman-Lab" target="_blank">Gustavo Goldman's team at São Paulo University in Brazil</a> and many other collaborators around the world have been collecting samples of fungi from patients infected with different species of <em>Aspergillus</em> molds. One of the species we are particularly interested in is <a href="https://doi.org/10.1006/rwgn.2001.0082" target="_blank"><em>Aspergillus nidulans</em>, a relatively common and generally harmless fungus</a>. Clinical laboratories typically identify the species of <em>Aspergillus</em> causing the infection by examining cultures of the fungi under the microscope. The problem with this approach is that very closely related species of <em>Aspergillus</em> tend to look very similar in their broad morphology or physical appearance when viewing them through a microscope.</p><p>Interested in examining the varying abilities of different <em>A. nidulans</em> strains to cause disease, we decided to analyze their total genetic content, or genomes. What we saw came as a total surprise. We had not collected <em>A. nidulans</em> but <em>Aspergillus latus</em>, a close relative of <em>A. nidulans</em> and, as we were to soon find out, <a href="https://doi.org/10.1016/j.cub.2020.04.071" target="_blank">a hybrid species that evolved through the fusion of the genomes</a> of two other <em>Aspergillus</em> species: <em>Aspergillus spinulosporus</em> and an unknown close relative of <em>Aspergillus quadrilineatus</em>. Thus, we realized not only that these patients harbored infections from an entirely different species than we thought they were, but also that this species was the first ever <em>Aspergillus</em> hybrid known to cause human infections.</p>
Several Different Fungal Hybrids Cause Human Disease.<p>Hybrid fungi that can cause infections in humans are well known to occur in several different lineages of single-celled fungi known as yeasts. Notable examples include multiple different species of <a href="https://doi.org/10.1002/yea.3242" target="_blank">yeast hybrids</a> that cause the human diseases <a href="https://rarediseases.info.nih.gov/diseases/6218/cryptococcosis" target="_blank">cryptococcosis</a> and <a href="https://www.cdc.gov/fungal/diseases/candidiasis/index.html" target="_blank">candidiasis</a>. Although pathogenic yeast hybrids are well known, our discovery that the <em>A. latus</em> pathogen is a hybrid is a first for molds that cause disease in humans.</p>
(Left) Candida yeasts live on parts of the human body. Imbalance of microbes on the body can allow these yeasts, some of which are hybrids, to grow and cause infection. (Right) Cryptococcus yeasts, including ones that are hybrids, can cause life-threatening infections in primarily immunocompromised people. Centers for Disease Control and Prevention<p><a href="https://doi.org/10.1371/journal.ppat.1008315" target="_blank">Why certain <em>Aspergillus</em> species are so deadly</a> while others are harmless remains unknown. This may in part be because <a href="https://doi.org/10.1016/j.fbr.2007.02.007" target="_blank">combinations of traits, rather than individual traits</a>, underlie organisms' ability to cause disease. So why then are hybrids frequently associated with human disease? Hybrids inherit genetic material from both parents, which may result in new combinations of traits. This may make them more similar to one parent in some of their characteristics, reflect both parents in others or may differ from both in the rest. It is precisely this mix and match of traits that hybrids have inherited from their parental species that <a href="https://www.nytimes.com/2010/09/14/science/14creatures.html" target="_blank">facilitates their evolutionary success</a>, including their ability to cause disease.</p>
The Evolutionary Origin of an Aspergillus Hybrid.<p>Multiple evolutionary paths can lead to the emergence of hybrids. One path is through mating, just as the horse and donkey mate to create a mule. Another path is through the merging or fusion of genetic material from cells of different species.</p><p>It is this second path that appears to have been taken by our fungus. <em>A. latus</em> appears to have two of almost everything compared to its parental species: twice the genome size, twice the total number of genes and so on. But unlike other hybrids, which are often sterile like the mule, we found that <em>A. latus</em> is capable of reproducing both asexually and sexually.</p><p>But how distinct were the parents of <em>A. latus</em>? By comparing the parts contributed by each parent in the <em>A. latus</em> genome, we estimate that its parents are approximately 93% genetically similar, which is about as related as we humans are with lemurs. In other words, <em>A. latus</em>, an agent of infectious disease, is the fungal equivalent of a human-lemur hybrid.</p>
How A. Latus Differs From its Parents.<p>Elucidating the identity of closely related fungal pathogens and how they differ from each other in infection-relevant characteristics is a key step toward reducing the burden of fungal disease. For example, we found that <em>A. latus</em> was three times more resistant than <em>A. nidulans</em>, the species it was originally identified as using microscopy-based methods, to one of the most common antifungal drugs, <a href="https://www.drugbank.ca/drugs/DB00520" target="_blank">caspofungin</a>. This result provides a clear example of the potential importance of accurate identification of the <em>Aspergillus</em> pathogen causing an infection.</p><p>We also examined how <em>A. latus</em> and <em>A. nidulans</em> interact with cells from our immune system. We found that immune cells were less efficient at combating <em>A. latus</em> compared to <em>A. nidulans</em>, suggesting the hybrid fungus may be trickier for our immune systems to identify and destroy.</p><p>In the midst of the COVID-19 pandemic, our quest to understand <em>Aspergillus</em> pathogens is becoming more urgent. Growing evidence suggests that <a href="https://doi.org/10.1111/myc.13096" target="_blank">a fraction of COVID-19 patients are also infected with <em>Aspergillus</em>.</a> More worrying is that these <a href="https://doi.org/10.3201/eid2607.201603" target="_blank">secondary <em>Aspergillus</em> infections</a> can worsen the clinical outcomes for those infected with the novel coronavirus. That being said, we stress that little is known about <em>Aspergillus</em> infections in COVID-19 patients due to a lack of systematic testing, and none of the infections identified so far appear to have been caused by hybrids.</p><p>So, when it comes to hybrids, some are fantastic (the minotaur), some are helpful (the mule) and some are dangerous (<em>Aspergillus latus</em>). Understanding more about the biology of <em>Aspergillus latus</em> may help in our understanding of how microbial pathogens arise and how to best prevent and combat their infections.</p>
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Growing Contribution<img lazy-loadable="true" src="https://assets.rebelmouse.io/eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJpbWFnZSI6Imh0dHBzOi8vYXNzZXRzLnJibC5tcy8yMzM3NDY5Ny9vcmlnaW4ucG5nIiwiZXhwaXJlc19hdCI6MTY0NjM4MTgyM30.IuQTKQs1stvYYKD6vaVTrqAyoBsUG0BhDvlhxsyKwPA/img.png?width=980" id="02a05" class="rm-shortcode" data-rm-shortcode-id="2841f82b1785df5d5ed7bf64d3bb882b" data-rm-shortcode-name="rebelmouse-image" />
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