Single Dose of 'Magic Mushrooms' Provides Long-Term Anxiety Relief for Cancer Patients, Study Suggests
Not only did the patients feel reductions in anxiety, a slew of other mental health symptoms were relieved as well, including depression, hopelessness, demoralization and death anxiety, according to CNN.
In addition to self-reported improved well-being or life satisfaction, some patients rated the treatment as being "among the most personally meaningful and spiritually significant experiences of their lives," the authors wrote, as Medscape Medical News reported.
The study, published in the Journal of Psychopharmacology, followed up on a study published in 2016 that gave cancer patients a single dose of synthetic psilocybin, the psychoactive chemical present in mushrooms, in a controlled setting where the patients were monitored the entire time, as NBC News reported.
The study was featured recently in the documentary Fantastic Fungi.
The new follow-up tracked 15 of the first 29 participants from the study nearly five years after their guided experience with synthetic psilocybin. After five years, nearly 80 percent were still experiencing significant improvements in cancer-related depression and anxiety. Furthermore, almost all of the participants chalked up their positive life changes to the psychedelic-assisted therapy, according to NBC News.
"Our findings strongly suggest that psilocybin therapy is a promising means of improving the emotional, psychological, and spiritual well-being of patients with life-threatening cancer," said Dr. Stephen Ross, associate professor of psychiatry in the Department of Psychiatry at NYU Langone Health, as CNN reported.
"This approach has the potential to produce a paradigm shift in the psychological and existential care of patients with cancer, especially those with terminal illness," Ross added, as Medscape Medical News reported.
That said, it is important to note that this was a single controlled-dose from pharmacy-made synthetic psilocybin, and a trained nurse monitored the patients while they were under the influence of the narcotic. Possessing hallucinogenic mushrooms is a felony and ingesting them is potentially hazardous.
The researchers are not sure why psilocybin produced such long-lasting relief, but they previously theorized that it has to do with the brain's neuroplasticity — the brain's ability to adapt and change with various experiences, according to CNN.
"These results may shed light on how the positive effects of a single dose of psilocybin persist for so long," said Gabby Agin-Liebes, lead investigator and lead author of the long-term follow-up study, and co-author of the 2016 parent study. "The drug seems to facilitate a deep, meaningful experience that stays with a person and can fundamentally change his or her mindset and outlook."
One of the patients, Dinah Bazer, suffered from ovarian cancer in her 60s. After a successful round of chemotherapy, her anxiety inexplicably overwhelmed her.
"I thought that when the chemo ended, I would celebrate but instead, I went into a tailspin. Even though my prognosis was really excellent, I was worried about a relapse," Bazer said to NBC News. After her experience with synthetic psilocybin, Bazer went through six-months of no anxiety at all.
"What is permanent is that I don't have anxiety about cancer. Not only about my cancer returning, but how I viewed my reoccurrence when it did happen," said Bazer, who was diagnosed last March with a type of rare gastrointestinal cancer, as NBC News reported.
While the results are promising, they are limited because of the small number of patients in the study and the follow-up.
"The conclusions that can be drawn are limited because the original trial was a crossover design," said James Rucker, who leads the Psychedelic Trials Group at the Centre for Affective Disorders at Kings College London in the UK, to CNN. "This means that in the original trial every participant eventually received psilocybin. Because of this, there is no control group in this current study. This means that we do not know whether the participants might have improved long term anyway, regardless of the treatment."
However, Ross sees a bright future for the future of psilocybin in oncology.
"This could profoundly transform the psycho-oncologic care of patients with cancer, and importantly could be used in hospice settings to help terminally ill cancer patients approach death with improved emotional and spiritual well-being," Ross said, as CNN reported.
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By John R. Platt
The straw-headed bulbul doesn't look like much.
It's less than a foot in length, with subdued brown-and-gold plumage, a black beak and beady red eyes. If you saw one sitting on a branch in front of you, you might not give it a second glance.
Cages line the Malang bird and animal market on Java in 2016. Andrea Kirkby / CC BY-SA 2.0
A kingfisher, looking a little worse for wear, in the Malang bird and animal market in 2016. Andrea Kirkby / CC BY-SA 2.0
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EcoWatch Daily Newsletter
By Julián García Walther
One morning in January, I found myself 30 feet up a tall metal pole, carrying 66 pounds of aluminum antennas and thick weatherproofed cabling. From this vantage point, I could clearly see the entire Punta Banda Estuary in northwestern Mexico. As I looked through my binoculars, I observed the estuary's sandy bar and extensive mudflats packed with thousands of migratory shorebirds frenetically pecking the mud for food.
There are currently few Motus stations in Mexico, leading to a large information gap. Julián García Walther / CC BY-ND
Red knots and many other shorebirds travel thousands of miles from breeding grounds in the Arctic (left) to nonbreeding grounds in Latin America (right). Julián García Walther / CC BY-ND
Motus stations require a high vantage point that overlooks estuaries. Julián García Walther / CC BY-ND
Any bird with a transmitter will be picked up if it flies within 12 miles (20 kilometers) of a Motus station. Julián García Walther / CC BY-ND<h2>Tagging Birds</h2><p>The stations alone can't detect these animals. The final step, which will happen in the coming months, is to catch birds and tag them. To do this, our team will set up a soft, spring-loaded net called a whoosh net in sandy areas where the red knots rest above the high-tide line. When birds walk past the net, the crew leader will release the trigger, <a href="https://www.youtube.com/watch?v=vwMiA2iqVc0" target="_blank" rel="noopener noreferrer">safely trapping the birds with the net</a>.</p>
WhooshNetCapture.MTS<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="6440038cdc58961906f5fa164b457688"><iframe lazy-loadable="true" src="https://www.youtube.com/embed/vwMiA2iqVc0?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span>
The world's oceans and coastal ecosystems can store remarkable amounts of carbon dioxide. But if they're damaged, they can also release massive amounts of emissions back into the atmosphere.
By Kimberly Nicole Pope
During this year's Davos Agenda Week, leaders from the private and public sectors highlighted the urgent need to halt and reverse nature loss. Deliberate action on the interlinked climate and ecological crises to achieve a net-zero, nature-positive economy is paramount. At the same time, these leaders also presented a message of hope: that investing in nature holds the key to ensuring economic and social prosperity and resilience.
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By Brett Wilkins
While some mainstream environmental organizations welcomed Tuesday's introduction of the CLEAN Future Act in the House of Representatives, progressive green groups warned that the bill falls far short of what's needed to meaningfully tackle the climate crisis—an existential threat they say calls for bolder action like the Green New Deal.
<div id="25965" class="rm-shortcode" data-rm-shortcode-id="6116a1c2b1b913ad51c3ea576f2e196c"><blockquote class="twitter-tweet twitter-custom-tweet" data-twitter-tweet-id="1366827205427425289" data-partner="rebelmouse"><div style="margin:1em 0">BREAKING: Rep @FrankPallone just released his CLEAN Future Act — which he claims to be an ambitious bill to combat… https://t.co/M7nR0es196</div> — Friends of the Earth (Action) (@Friends of the Earth (Action))<a href="https://twitter.com/foe_us/statuses/1366827205427425289">1614711974.0</a></blockquote></div>
<div id="189f0" class="rm-shortcode" data-rm-shortcode-id="aa31bacec80d88b49730e8591de5d26d"><blockquote class="twitter-tweet twitter-custom-tweet" data-twitter-tweet-id="1366863402912657416" data-partner="rebelmouse"><div style="margin:1em 0">The CLEAN Future Act "fails to grasp the fundamental truth of fighting climate change: We must stop extracting and… https://t.co/yREn6Qx9tn</div> — Food & Water Watch (@Food & Water Watch)<a href="https://twitter.com/foodandwater/statuses/1366863402912657416">1614720605.0</a></blockquote></div>
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