Researchers at the pharmaceutical giant Eli Lilly announced yesterday that it will start a trial on a new drug designed specifically for COVID-19, a milestone in the race to stop the infectious disease, according to STAT News.
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By Cathy Cassata
With more than 1.7 million confirmed cases of COVID-19 in the United States and more than 100,000 deaths from the virus, physicians face unprecedented challenges in their efforts to keep Americans safe.
They also encounter what some call an "infodemic," an outbreak of misinformation that's making it more difficult to treat patients.
When Leaders and Doctors Spread Misinformation<p>When people in charge of towns, cities, states, and countries spread misinformation, the potential for belief in misinformation to result in policies can have harmful effects.</p><p><a href="https://www.northwell.edu/find-care/find-a-doctor?q=Bruce+E.+Hirsch%2C+MD&insurance=&location=&query_type=provider&physician_partners=false&default_view=list&gender=&language=&sort=relevancy" target="_blank">Dr. Bruce E. Hirsch</a>, attending physician and assistant professor in the infectious disease division of Northwell Health in Manhasset, New York, says an example of this is when President Trump informed the public he was taking hydroxychloroquine as a preventive measure.</p><p>"To approach this enormous challenge, we need some intellectual honesty and clarity, and to disregard expertise and to make decisions and model decisions based on hunches is inviting us to handle challenges on the basis of rumor and uninformed opinion. The magnitude of that error is epic," Hirsch told Healthline.</p><p>Stukus agrees, noting that the harm of this proclamation is documented.</p><p>"Early on when the president touted the benefits of hydroxychloroquine and azithromycin, people started to hoard this medicine, and state boards had to shut it down because they were getting so many prescriptions for this unproven therapy that it was not available for those who truly needed it, such as those who have lupus and autoimmune conditions," Stukus said.</p><p>He adds that calls to poison control centers increased after the president suggested using disinfectant to prevent contracting the new coronavirus.</p>
Listen to Science, Even When it Changes<p>When recommendations change or evidence flip-flops, skepticism may arise. However, Stukus says change is the beauty of science.</p><p>"That shows us that we can evolve, and if the evidence shows that our prior thoughts were incorrect, we need to be able to change our recommendations and advice based upon the best quality of evidence at the time," he said.</p><p>Pierre agrees.</p><p>"Science is an iterative process, whereby we arrive at facts and truth through repeated and controlled observations. That means that it's inherently self-correcting as we revise conclusions based on ongoing research. Scientific facts aren't immutable dogma chiseled on a tablet. They change based on the best available evidence we have at a given point in time," he said.</p><p>Because research of COVID-19 has only been underway for 6 months, information is evolving rapidly, and new information may contradict old.</p><p>"There's still much we don't know about exactly how [COVID-19] spreads, what effects it has on the body, or how to best treat it. That means that the best available evidence is preliminary, but that doesn't mean that we should ignore it or turn to other sources of information or opinion as if they're just as valid," Pierre said.</p><p>He explains that conspiracy theories based on mistrust lead to vulnerability to misinformation.</p><p>If people mistrust science because it sometimes "changes its mind," Pierre said, "that shouldn't be used to embrace other opinions based on no evidence at all, which are typically selected based on confirmation bias: what we want to believe rather than what the objective evidence supports."</p>
Where to Find the Best Information<p>Stukus says to start with the <a href="https://www.cdc.gov/coronavirus/2019-nCoV/index.html" target="_blank">CDC</a> and <a href="https://www.nih.gov/health-information/coronavirus" target="_blank">NIH</a>. Then check with your local health officials, because COVID-19 guidelines may vary depending on where you live.</p><p>If you can't find information you need or have questions specifically related to you, call your primary care doctor.</p><p>"Your personal doctor should always be a resource for individual specific questions because they know best how to apply all the nuances retaining to your health, and how to incorporate all the other general [COVID-19] recommendations," Stukus said.</p><p><a href="https://www.eehealth.org/find-a-doctor/b/boyd-laura-b/" target="_blank">Dr. Laura Boyd</a>, primary care physician at Edward-Elmhurst Health Center in Elmhurst, Illinois, says her clinic receives a lot of calls about COVID-19.</p><p>"Most doctors' offices are receiving calls and answering questions, and doing phone or video visits to help clarify and/or order testing over the phone based on patients' symptoms. It is always best to call your doctor's office first instead of worrying about symptoms and waiting too long to seek treatment," she told Healthline.</p><p>If your primary care doctor has limited testing, she suggests looking on your state's public health website for available testing sites.</p><p>With a lot of unknowns related to this virus and disease, Boyd says many patients are feeling overwhelmed and anxious for a treatment.</p><p>"Unfortunately, there is no specific medication recommended for COVID for outpatient. There are a lot of ongoing studies with various drugs going on within the hospital setting. Patients should always contact their doctors about their specific symptoms as they can treat the symptoms that go along with COVID, but there is no cure," Boyd said.</p><p>While we wait for treatment and a vaccine, Hirsch, who treats patients hospitalized for COVID-19 complications on a daily basis, says everyone can do their part by washing hands, wearing a mask, and staying 6 feet apart.</p><p>"As an infectious disease doctor working in the hospital, I see the damage of the pandemic and the worst cases of what's happening. We are trying to get the best possible outcome and confronting this overwhelming biologic reality of this terrible epidemic the best we can," Hirsch said.</p><p>Everyone at home can help in the fight too, he adds.</p><p>"Follow information that is science- and evidence-based, and avoid that which is not," he said.</p>
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EcoWatch Daily Newsletter
The nationwide horror at the killing of George Floyd by the Minneapolis police has triggered protests in 75 cities. People are demonstrating against the systemic racism that has made people of color targets of lethal actions by law enforcement. In response, elected officials and public health experts are walking a fine line of affirming the rights of protestors while simultaneously worrying that the protests will lead to a new wave of coronavirus infections.
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The total number of confirmed coronavirus cases passed six million Sunday, even as many countries begin to emerge from strict lockdowns.
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By Julia Ries
Around the world, there have been several cases of people recovering from COVID-19 only to later test positive again and appear to have another infection.
The Viral Material in Re-Positive Cases Isn’t Infectious<p>The Korean study examined 285 patients who tested positive again for the new coronavirus after they recovered from COVID-19, which had been confirmed via a negative test result.</p><p>The researchers swabbed the patients and examined the viral material to determine whether it was still actively infectious.</p><p>The team was unable to isolate live viral material, indicating that the positive diagnostic tests were picking up dead virus particles.</p><p>"[This] may speak for the fact that the virus may be dead or not be fit enough to grow — therefore the virus may not be fit enough to infect a new host," said <a href="http://www.providence.org/doctors/profile/1099717-andres-romero" target="_blank">Dr. Andres Romero</a>, an infectious disease specialist at Providence Saint John's Health Center in Santa Monica, California.</p><p>The researchers also tested 790 people who'd been in close contact with the "re-positive" patients. Of the 27 who tested positive, no cases appeared to be caused from exposure to someone who appeared to have a reinfection.</p><p>The report also found that the vast majority of recovered patients (96 percent) had neutralizing antibodies, indicating that they conferred immunity.</p><p>"Whether this is indicative of a completely protective response remains to be proven. If this study holds true, then people who have recovered can get back to work," Zapata said.</p><p>In response to the new findings, South Korea eliminated a policy requiring discharged patients to isolate for 2 weeks.</p>
Conducting and Interpreting PCR Tests<p>The tests widely used to diagnose COVID-19 are called polymerase chain reaction (PCR) tests.</p><p>The tests swab a person's nose or throat and try to pick up the virus's genetic material, or RNA.</p><p>According to <a href="https://www.cdc.gov/coronavirus/2019-ncov/hcp/faq.html" target="_blank">guidance</a> from the U.S. Centers for Disease Control and Prevention (CDC), a positive result on a PCR test doesn't "necessarily mean infectious virus is present or that the patient is contagious."</p><p>Infectious disease experts have suspected that the test kits aren't picking up actively infectious viral material in recovered patients who test positive again, but rather dead remnants of the virus.</p><p>We see this occur with other viruses, too.</p><p>"We know other viruses like parainfluenza, human metapneumovirus, or RSV [respiratory syncytial virus] may linger for months in certain patients, and that does not represent infectious state," Romero said. "Coronavirus may be the same."</p>
We Still Need to Practice Caution<p>While the findings are promising, infectious disease experts say we still need to practice caution.</p><p>More research is needed to validate these findings and determine whether they apply to distinct parts of the population, such as those who are immunocompromised.</p><p>It's common for immunocompromised patients — such as those with cancer — to continue testing positive for a virus for longer, since it takes their immune system more time to clear the virus out of their body.</p><p>"I don't think we can be 100 percent certain of whether each recovered person is no longer contagious. Again, this may differ with distinct population groups," Zapata said.</p><p>Physicians are seeing some hospitalized patients testing positive for a month after they were first swabbed for COVID-19. It's unclear whether these patients still shed infectious virus, according to Zapata.</p><p>Everyone's body mounts a distinct immune response based on their age and overall health. Different individuals will clear the virus out at different speeds, according to Zapata.</p><p>Until we have more data and a preventive vaccine, it's crucial to continue adhering to the <a href="https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/prevention.html" target="_blank">safety precautions</a> laid out by the CDC.</p><p>"The reality is that moving forward, the best approach will be keeping social/physical distancing, wearing a mask, and frequent hand hygiene in order to control the spread of the virus," Romero said.</p>
The Bottom Line<p>Doctors and researchers have been unsure whether people who recover from COVID-19 who test positive again continue to be contagious, or if they could get a second infection.</p><p>New <a href="https://www.cdc.go.kr/board/board.es?mid=a30402000000&bid=0030" target="_blank">research</a> published by the Korea Centers for Disease Control and Prevention has found that recovered COVID-19 patients who test positive again aren't infectious.</p><p>The study also found that most patients who recover have neutralizing antibodies that protect them from getting sick again.</p><p>Though the study is promising, health experts say we need more data to validate the findings and determine whether they apply to all patient populations.</p>
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By Tara Lohan
The first official tallies are in: Coronavirus-related shutdowns helped slash daily global emissions of carbon dioxide by 14 percent in April. But the drop won't last, and experts estimate that annual emissions of the greenhouse gas are likely to fall only about 7 percent this year.
What lessons can we learn from your research to guide us right now, in what seems like a really critical time in the fight to halt climate change?<p>What a lot of people don't understand is that to limit warming to 1.5 degrees Celsius, we actually have to reduce emissions by around 7-8 percent <em>every single year</em> from now until 2030, which is what the emissions drop is likely to be this year because of the COVID-19 crisis.</p><p>So think about what it took to reduce emissions by that much and think about how we have to do that <em>every single year</em>.</p><p>It doesn't mean that it's going to be some big sacrifice, but it does mean that we need government policy, particularly at the federal level, because state policy can only go so far. We've been living off state policy for more than three decades now and we need our federal government to act.</p>
Where are we now, in terms of our progress on renewable energy and how far we need to go?<p>A lot of people think renewable energy is growing "so fast" and it's "so amazing." But first of all, during the coronavirus pandemic, the renewable energy industry is actually doing very poorly. It's losing a lot of jobs. And secondly, we were not moving fast enough even before the coronavirus crisis, because renewable energy in the<em> best </em>year grew by only 1.3 percent.</p><p>Right now we're at around 36-37 percent clean energy. That includes nuclear, hydropower and new renewables like wind, solar and geothermal. But hydropower and nuclear aren't growing. Nuclear supplies about 20 percent of the grid and hydro about 5 percent depending on the year. And then the rest is renewable. So we're at about 10 percent renewables, and in the best year, we're only adding 1 percent to that.</p><p>Generally, we need to be moving about eight times faster than we've been moving in our best years. (To visualize this idea, I came up with the <a href="https://grist.org/fix/how-quickly-do-we-need-to-ramp-up-renewables-look-to-the-narwhal/" target="_blank">narwhal curve</a>.)</p>
How do we overcome these fundamental issues of speed and scale?<p>We need actual government policy that supports it. We have never had a clean electricity standard or renewable portfolio standard at the federal level. That's the main law that I write all about at the state level. Where those policies are in place, a lot of progress has been made — places like California and even, to a limited extent, Texas.</p><p>We need our federal government to be focusing on this crisis. Even the really small, piecemeal clean-energy policies we have at the federal level are going away. In December Congress didn't extend the investment tax credit and the production tax credit, just like they didn't extend or improve the electric vehicle tax credit.</p><p>And now during the COVID-19 crisis, a lot of the money going toward the energy sector in the CARES Act is going toward propping up <a href="https://www.bloomberg.com/news/articles/2020-05-15/-stealth-bailout-shovels-millions-of-dollars-to-oil-companies" target="_blank">dying fossil fuel companies</a> and not toward supporting the renewable energy industry.</p><p>So we are moving in the wrong direction.</p>
Clean energy hasn’t always been such a partisan issue. Why did it become so polarizing?<p>What I argue in my book, with evidence, is that electric utilities and fossil fuel companies have been intentionally driving polarization. And they've done this in part by running challengers in primary elections against Republicans who don't agree with them.</p><p>Basically, fossil fuel companies and electric utilities are telling Republicans that you can't hold office and support climate action. That has really shifted the incentives within the party in a very short time period.</p><p>It's not like the Democrats have moved so far left on climate. The Democrats have stayed in pretty much the same place and the Republicans have moved to the right. And I argue that that's because of electric utilities and fossil fuel companies trying to delay action.</p>
And their reason for doing that is simply about their bottom line and keeping their share of the market?<p>Exactly. You have to remember that delay and denial on climate change is a profitable enterprise for fossil fuel companies and electric utilities. The longer we wait to act on the crisis, the more money they can make because they can extract more fossil fuels from their reserves <em>and</em> they can pay more of their debt at their coal plants and natural gas plants. So delay and denial is a money-making business for fossil fuel companies and electric utilities.</p>
There’s been a lot of research, reporting and even legal action in recent years about the role of fossil fuel companies in discrediting climate science. From reading your book, it seems that electric utilities are just as guilty. Is that right?<p>Yes, far less attention has been paid to electric utilities, which play a really critical role. They preside over legacy investments into coal and natural gas, and some of them continue to propose building new natural gas.</p><p>They were just as involved in promoting climate denial in the 1980s and 90s as fossil fuel companies, as I document in my book. And some of them, like Southern Company, have continued to promote climate denial to basically the present day.</p><p>But that's not the only dark part of their history.</p><p>Electric utilities promoted energy systems that are pretty wasteful. They built these centralized fossil fuel power plants rather than having co-generation plants that were onsite at industrial locations where manufacturing is happening, and where you need both steam heat — which is a waste product from electricity — and the electricity itself. That actually created a lot of waste in the system and we burned a lot more fossil fuels than if we had a decentralized system.</p><p><span></span>The other thing they've done in the more modern period is really resisted the energy transition. They've resisted renewable portfolio standards and net metering laws that allow for more clean energy to come onto the grid. They've tried to roll them back. They've been successful in some cases, and they've blocked new laws from passing when targets were met.</p>
You wrote that, “Partisan polarization on climate is not inevitable — support could shift back to the bipartisanship we saw before 2008.” What would it take to actually make that happen?<p>Well, on the one hand, you need to get the Democratic Party to care more about climate change and to really understand the stakes. And if you want to do that, I think the work of the <a href="https://www.justicedemocrats.com/" target="_blank">Justice Democrats</a> is important. They have primary-challenged incumbent Democrats who don't care enough about climate change. That is how Alexandria Ocasio-Cortez was elected. She was a primary challenger and she has really championed climate action in the Green New Deal.</p><p>The other thing is that the public supports climate action. Democrats do in huge numbers. Independents do. And to some extent Republicans do, particularly young Republicans.</p><p>So communicating the extent of public concern on these issues is really important because, as I've shown in other research, politicians don't know how much public concern there is on climate change. They dramatically underestimate support for climate action.</p><p>I think the media has a really important role to play because it's very rare that a climate event, like a disaster that is caused by climate change, is actually linked to climate change in media reporting.</p><p>But people might live through a wildfire or a hurricane or a heat wave, but nobody's going to tell them through the media that this is climate change. So we really need our reporters to be doing a better job linking people's lived experiences to climate change.</p>
With economic stimulus efforts ramping up because of the COVD-19 pandemic, are we in danger of missing a chance to help boost a clean energy economy?<p>I think so many people understand that stimulus spending is an opportunity to rebuild our economy in a way that creates good-paying jobs in the clean-energy sector that protects Americans' health.</p><p>We know that <a href="https://www.bbc.com/future/article/20200427-how-air-pollution-exacerbates-covid-19" target="_blank">breathing dirty air</a> makes people more likely to die from COVID-19. So this is a big opportunity to create an economy that's more just for all Americans.</p><p>But unfortunately, we really are not pivoting toward creating a clean economy, which is what we need to be doing. This is an opportunity to really focus on the climate crisis because we have delayed for more than 30 years. There is not another decade to waste.</p>
By Jon Queally
President Donald Trump at a White House press conference on Friday announced he was "terminating" ties to the World Health Organization, even as the global death toll from the coronavirus pandemic nears 363,000 — including the more than 100,000 dead from the virus in the U.S., many attributed to his own mismanagement of the crisis.
The office may never look the same again. And the investment it will take to protect employees may force many companies to go completely remote. That's after the Centers for Disease Control and Prevention (CDC) issued new recommendations for how workers can return to the office safely.
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By Richard Connor
The University of Southern Denmark on Wednesday announced that its researchers have developed the world's first fully automatic robot capable of carrying out throat swabs for COVID-19.
By Jory Brinkerhoff
Summer is field season for ecologists like me, a time when my colleagues, students and I go out into fields and woods in search of ticks to study the patterns and processes that allow disease-causing microbes – primarily bacteria and viruses – to spread among wildlife and humans.
Delaying Medical Treatment Can Be Dangerous<p>As we move from spring into summer, and into the peak period of tick activity in much of the Northern Hemisphere, time spent outdoors will increase, as will risk of tick-transmitted disease.</p><p>In some cases, there are key symptoms of a tick-transmitted disease that can help with diagnosis. For example, early Lyme disease, which is caused by the bite of an infected black-legged tick, sometimes called the deer tick, is commonly associated with an expanding "bull's-eye rash." <a href="https://www.cdc.gov/lyme/signs_symptoms/index.html" target="_blank">Seventy percent to 80% of patients have this symptom</a>.</p><p>However, <a href="https://www.cdc.gov/lyme/signs_symptoms/index.html" target="_blank">other symptoms</a> of Lyme disease – fever, head and body aches and fatigue – are less distinctive and can be easily confused with other illnesses, including COVID-19. This can make it more difficult to diagnose a patient who did not notice a rash or was unaware that they ever had a tick bite. As a result, Lyme disease cases can be <a href="http://doi.org/10.4081/or.2011.e14" target="_blank">misdiagnosed</a>. Nationally, Lyme disease may be undercounted to the point that only <a href="https://www.cdc.gov/lyme/datasurveillance/index.html" target="_blank">one in 10 cases is reported to the CDC</a>.</p>
Lyme Disease Isn’t the Only Tick Problem<p>Lyme disease is most common in the Northeast and North Central U.S., but that does not mean that people in areas without Lyme disease are free from worry about tick-transmitted disease. Ticks throughout North America can spread a <a href="https://www.cdc.gov/ticks/tickbornediseases/index.html" target="_blank">wide range of diseases,</a> many of which also present with flu-like symptoms, leading to the potential for <a href="https://doi.org/10.1016/j.ttbdis.2015.06.005" target="_blank">misdiagnosis</a>, especially when these diseases are not especially common in the general population.</p>
Is COVID-19 Increasing Chances of Tick Bites?<p><a href="https://www.scientificamerican.com/article/how-the-coronavirus-has-changed-animals-landscape-of-fear/" target="_blank">Recent reports</a> from across the nation and around the globe suggest that wildlife have become more bold this spring, wandering into suburbs and cities where human and vehicle traffic are reduced because of COVID-19.</p><p>Whether this phenomenon is being driven by changes in animal behavior or is simply an artifact of humans spending <a href="https://www.popsci.com/story/environment/wildlife-in-cities-covid-shutdown/" target="_blank">more time in their homes and becoming more aware of their surroundings</a> is not clear, but changes in wildlife behavior and habitat use could affect tick-transmitted disease. For example, white-tailed deer are important hosts to multiple human-biting tick species in eastern North America, including black-legged ticks, and more deer around our homes and in our neighborhoods could lead to more ticks that have a chance to bite humans.</p>
Staying Safe<p>Awareness is a key component of preventing and treating tick-borne disease. People should be aware of the activities that could <a href="https://www.cdc.gov/lyme/prev/index.html" target="_blank">expose them to ticks</a>, and <a href="https://pubmed.ncbi.nlm.nih.gov/10780095/" target="_blank">physicians should consider the possibility of tick-borne disease</a>, especially given the potential overlap in symptoms with COVID-19.</p><p>As with COVID-19, mitigation efforts can <a href="https://www.cdc.gov/lyme/prev/on_people.html" target="_blank">substantially reduce the risk</a> of tick-borne diseases. Wear long sleeves and long pants and use an <a href="https://www.epa.gov/insect-repellents" target="_blank">EPA-registered repellent</a> when you are in tick habitat, and check yourself thoroughly for ticks when you get home.</p><p>It is important to be aware of ticks when spending time outside, but fear of ticks should not stop people from enjoying nature. </p>
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A Tyson Foods pork plant in Storm Lake, Iowa announced it would close Thursday after more than 20 percent of its workforce tested positive for the new coronavirus.
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