Meet Elizabeth Ann, the First U.S. Endangered Species to Be Cloned
The clone in question is a black-footed ferret named Elizabeth Ann, and her lineage could bring much needed genetic diversity to the imperiled species.
"[I]t was a commitment to seeing this species survive that has led to the successful birth of Elizabeth Ann," Ryan Phelan, the executive director of biotechnology conservation nonprofit Revive and Restore, said in a Fish and Wildlife Service (FWS) press release. "To see her now thriving ushers in a new era for her species and for conservation-dependent species everywhere. She is a win for biodiversity and for genetic rescue."
Cutting-edge science and a blast from the past! Meet Elizabeth Ann. She’s the first-ever cloned black-footed ferret… https://t.co/L4SShmmXOQ— US Fish and Wildlife (@US Fish and Wildlife)1613669102.0
Elizabeth Ann's birth was a joint effort from FWS, Revive and Restore, ViaGen Pets and Equine, San Diego Zoo Global and the Association of Zoos and Aquariums. She arrived on Dec. 10, with the birth first announced on Thursday.
The history of the black-footed ferret makes her birth an especially important milestone. The species once lived throughout the U.S. West, FWS recovery coordinator Pete Gober told The New York Times. But their numbers dwindled as their primary prey, prairie dogs, also declined due to habitat loss, poison and disease. At one point, scientists believed the black-footed ferret to be extinct.
"We thought they were gone," Gober told The New York Times.
That changed in 1981, when a ranch dog named Shep dragged one back to his owners' home in Wyoming. However, disease wiped out much of the newly discovered ranch population. The FWS captured 18 ferrets for a breeding program, but all of the ferrets they have bred and released since have come from just seven parents.
That's where Elizabeth Ann fits in. She is a clone of Willa, one of the last wild-caught black-footed ferrets whose genes were never passed on, according to FWS. However, they were preserved by the San Diego Zoo Global's Frozen Zoo in 1988, making Elizabeth Ann's birth possible.
"With these cloning techniques, you can basically freeze time and regenerate those cells," Gober told The Associated Press.
Scientists determined that her genome had triple the unique variations of the current ferret population, meaning that Elizabeth Ann's descendants could play a role in boosting the species' genetic health, according to FWS.
That won't happen right away, The New York Times reported. First, Elizabeth Ann will be joined by other Willa clones, as well as clones of a male named Studbook Number 2. The clones will breed, while their offspring will be interbred with wild ferrets. Scientists need to make sure that none of the mitochondrial DNA from the clones' surrogate mother, a domestic ferret, is passed on.
Cloning, which involves copying the genes of one plant or animal to make a new one, is emerging as a conservation strategy for imperiled species. Viagen, a Texas-based company that helped clone Willa, also cloned a Przewalski's wild horse last summer, The Associated Press reported. The Przewalski is a Mongolian horse species whose population of around 2,000 is descended from only 12 animals.
Cloning could also recover extinct animals. Ben Novak, Revive and Restore's lead scientist, wants to bring back the passenger pigeon, and the nonprofit is also looking into cloning a wooly mammoth. Some conservationists argue that these efforts take funding away from protecting existing species, The New York Times reported. But Novak argued that the genetic technology required for both de-extinction and conservation is the same.
The FWS also noted that it is not abandoning more traditional conservation efforts.
"Successful genetic cloning does not diminish the importance of addressing habitat-based threats to the species or the Service's focus on addressing habitat conservation and management to recover black-footed ferrets," Noreen Walsh, director of the Service's Mountain-Prairie region, said in the press release.
By Kate Whiting
From Greta Thunberg to Sir David Attenborough, the headline-grabbing climate change activists and environmentalists of today are predominantly white. But like many areas of society, those whose voices are heard most often are not necessarily representative of the whole.
1. Wangari Maathai<p>In 2004, Professor Maathai made history as the <a href="https://www.nobelpeaceprize.org/Prize-winners/Prizewinner-documentation/Wangari-Maathai" target="_blank" rel="noopener noreferrer">first African woman to be awarded the Nobel Peace Prize</a> for her dedication to sustainable development, democracy and peace. She started the <a href="http://www.greenbeltmovement.org/" target="_blank" rel="noopener noreferrer">Green Belt Movement</a>, a community-based tree planting initiative that aims to reduce poverty and encourage conservation, in 1977. More than 51 million trees have been planted helping build climate resilience and empower communities, especially women and girls. Her environmental work is celebrated every year on <a href="http://www.greenbeltmovement.org/node/955" target="_blank" rel="noopener noreferrer">Wangari Maathai Day on 3 March</a>.</p>
2. Robert Bullard<p>Known as the 'father of environmental justice,' Dr Bullard has <a href="https://www.unep.org/championsofearth/laureates/2020/robert-bullard" target="_blank">campaigned against harmful waste</a> being dumped in predominantly Black neighborhoods in the southern states of the U.S. since the 1970s. His first book, Dumping in Dixie, highlighted the link between systemic racism and environmental oppression, showing how the descendants of slaves were exposed to higher-than-average levels of pollutants. In 1994, his work led to the signing of the <a href="https://www.nrdc.org/experts/albert-huang/20th-anniversary-president-clintons-executive-order-12898-environmental-justice" target="_blank">Executive Order on Environmental Justice</a>, which the <a href="https://www.whitehouse.gov/briefing-room/presidential-actions/2021/01/27/executive-order-on-tackling-the-climate-crisis-at-home-and-abroad/" target="_blank">Biden administration is building on</a>.<br></p>
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Pollution has a race problem. Elizabethwarren.com
3. John Francis<p>Helping the clean-up operation after an oil spill in San Francisco Bay in January 1971 inspired Francis to <a href="https://planetwalk.org/about-john/" target="_blank" rel="noopener noreferrer">stop taking motorized transport</a>. Instead, for 22 years, he walked everywhere. He also took a vow of silence that lasted 17 years, so he could listen to others. He has walked the width of the U.S. and sailed and walked through South America, earning the nickname "Planetwalker," and raising awareness of how interconnected people are with the environment.</p>
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4. Dr. Warren Washington<p>A meteorology and climate pioneer, Dr. Washington was one of the first people to develop atmospheric computer models in the 1960s, which have helped scientists understand climate change. These models now also incorporate the oceans and sea ice, surface water and vegetation. In 2007, the <a href="https://www.cgd.ucar.edu/pcm/" target="_blank" rel="noopener noreferrer">Parallel Climate Model (PCM)</a> and <a href="https://www.cesm.ucar.edu/" target="_blank" rel="noopener noreferrer">Community Earth System Model (CESM)</a>, earned Dr. Washington and his colleagues the <a href="https://www.nobelprize.org/prizes/peace/2007/summary/" target="_blank" rel="noopener noreferrer">Nobel Peace Prize</a>, as part of the <a href="https://www.ipcc.ch/" target="_blank" rel="noopener noreferrer">Intergovernmental Panel on Climate Change</a>.</p>
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5. Angelou Ezeilo<p>Huge trees and hikes to pick berries during her childhood in upstate New York inspired Ezeilo to become an environmentalist and set up the <a href="https://gyfoundation.org/staff/Angelou-Ezeilo" target="_blank" rel="noopener noreferrer">Greening Youth Foundation</a>, to educate future generations about the importance of preservation. Through its schools program and Youth Conservation Corps, the social enterprise provides access to nature to disadvantaged children and young people in the U.S. and West Africa. In 2019, Ezeilo published her book <em>Engage, Connect, Protect: Empowering Diverse Youth as Environmental Leaders</em>, co-written by her Pulitzer Prize-winning brother Nick Chiles.</p>
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