Feb. 15, 2017 04:19PM EST
Uncovered documents show that the U.S. Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC) knew that infant vaccines were exposing American children to mercury far in excess of all federal safety guidelines since 1999. The documents, created by a FDA consulting toxicologist, show how federal regulators concealed the dangerous impacts and lied to the public.
In November 2016, I reported on six studies that found strong relationships between biomarkers for mercury toxicity in children with autism including a direct correlation between the levels of mercury toxicity and the severity of autism symptoms. Those findings are supported by recent research that links industrial exposures of lead, mercury and arsenic to the prevalence of autism spectrum disorder (ASD).
A Nov. 19 study, of 45,231 women, published in JAMA Pediatrics, identified a heightened risk of autism spectrum disorder (ASD) diagnosis in the children of mothers who received a flu shot during their first trimester of pregnancy. The study, Association Between Influenza Infection and Vaccination During Pregnancy and Risk of Autism Spectrum Disorder, was authored by Ousseny Zerbo and his colleagues affiliated with the Division of Research at Kaiser Permanente.
Two new studies by international teams, including Egyptian scientists, have validated the link between autism and mercury.
In an article published in the journal Metabolic Brain Disease, a team of nine scientists from leading Egyptian universities and medical schools confirmed the causal role of mercury in the onset of autism.
At least six American studies have linked autism presence or severity to mercury exposure as determined by measuring urinary porphyrins.
The scientists determined the extent of mercury poisoning in children by measuring urinary excretion of organic compounds called porphyrins, which act as biomarkers for mercury toxicity. The researchers also measured blood levels of mercury and lead. The researchers found a strong relationship between mercury toxicity and the presence of autism and a direct correlation between levels of mercury toxicity and the severity of autism symptoms.
The scientists studied 100 children; 40 with autism spectrum disorder (ASD), 40 healthy individuals and 20 healthy siblings of ASD children. The results showed that the children with ASD had significantly higher mercury levels than healthy children and healthy siblings. Children with the highest mercury levels had the most severe autism symptoms.
At least six American studies have linked autism presence or severity to mercury exposure as determined by measuring urinary porphyrins. The first study, completed by Heyer et al. in 2012 (Autism Res 5:84) showed a correlation between the presence of autism and specific urinary porphyrins associated with mercury toxicity. This affirmed an earlier study by Kern et al. (2011, Pediatr Int 53:147) where specific porphyrins associated with mercury toxicity were significantly higher in ASD children as compared to non-autistic controls. Woods et al. (2010, Environ Health Perspect 118:1450) also saw disordered porphyrin metabolism in autistic kids which was not observed in non-autistic control children. This again suggested increased mercury toxicity associated with autism and autism spectrum disorder.
Autism severity has also been correlated to levels of specific porphyrins associated with mercury toxicity. Kern et al. in 2010 (Biometals 23:1043) showed a strong relationship between the level of autism severity as measured by the Autism Treatment Evaluation Checklist (ATEC) instrument and the amount of urinary porphyrins observed in ASD children. Geier et al. (2009, J Toxicol Environ Health A 72:1585) also correlated urinary porphyrins to autism severity in a blind study using the childhood autism rating scale (CARS). This study was further elucidated by Geier et al. (2009, J Neurol Sci 15:280) where children with severe autism showed significantly higher urinary porphyrins associated with mercury toxicity as compared to those children with mild autism and non-autistic controls. Other biomarkers measured in this study correlating mercury toxicity with autism severity include the presence of glutathione, cysteine and sulfate metabolites in plasma.
In a second study, by Mostafa et al., published in Metabolic Brain Disease in June 2016, an international team of Egyptian, Norwegian, Saudi Arabian and Chilean physicians and scientists used a different set of measurement protocols to find a direct correlation between mercury levels and autism diagnosis. The reasearchers measured levels of neurokinin A and B - pro-inflammatory neuro peptides that indicate the presence of mercury in the blood – in 84 children with ASD and 84 controls. The results showed a positive linear relationship between mercury levels and the severity of autism symptoms.
Many of the mothers of children in the first 2016 Egyptian study (Khaled et al.) had multiple dental amalgams which may have contributed to the children's body levels of mercury. The study does not examine the potential link between autism and the vaccine preservative, thimerosal, which is 50 percent ethyl mercury by weight. However, other studies indicate that the ethyl mercury in thimerosal is 50 times as toxic to human tissue as the methylmercury in amalgams and fish (Guzzi et al. 2012, Interdiscipl Toxicol 5:159) and at least twice as persistent in the brain (Burbacher et al. 2005, Environ Health Perspect 113:1015).
The 2016 Metabolic Brain Disease studies are only the latest in a series of important studies by leading Egyptian doctors and scientists linking mercury exposure to autism. A September 2015 paper published in Behavioral Neurology (Mohamed et al. 2015, PMID 26508811) by a group of researchers from the faculty of Cairo's Ain Shams University and the National Institute of Standards studied 100 autistic children and 100 healthy children. The researchers found significantly high levels of mercury, lead and aluminum in the autistic children (probably from maternal fish consumptions, living near gas stations and usage of aluminum paints) and concluded that "environmental exposure to these toxic metals at key times in development may play a causal role in autism."
A November 2014 study published in Environmental Toxicology and Pharmacology (38:1016) by Heba Yassa of the Assuit University Medical School's Department of Forensic Medicine and Clinical Toxicology, looked at 45 children with autism and 45 controls. Using blood and hair samples, Dr. Yassa also found high levels of lead and mercury among the children with autism and not the controls. Using dimercaptosuccinic acid or DMSA as a chelating agent, Dr. Yassa was able to reduce blood mercury and lead levels in the autistic children. His study documents significant declines in autism symptoms with the decrease of metals in the children's blood. The study's concluded: "Lead and mercury are considered as one of the main causes of autism. Environmental exposure as well as genetic inability of certain individuals to excrete metals is responsible for the high levels of heavy metals. Detoxification by chelating agents had a great role in improving those kids."
Dr. Yassa's study duplicated the results of numerous previous peer-reviewed papers and case studies. For example, Blaucok-Busch et al. 2012 Maedica 7:214 and Adams et al. 2009 BMC Clinical Pharmacol 9:17 documents improvements in autism symptoms and even loss of the autism diagnosis following mercury chelation.
Dr. Yassa's 2014 study supported earlier findings by a team of German and Egyptian government and university medical school scientists, which reported in a 2012 study published in Maedica, a Journal of Clinical Medicine (Blaucok-Busch et al. 7:214). The scientists studied the efficacy of DMSA chelation therapy in a sample of Arab children with autism spectrum disorder. That study found that oral DMSA chelation in 44 children with autism ages 3 to 9 reduced body burden of three metals—cadmium, mercury and lead—and that detoxification reduced their behavioral effects and neurological symptoms of autism.
These 2014 and 2012 Egyptian studies supported the findings of several other publications and case studies, suggesting that heavy metal chelation has a measurable therapeutic effect on autism. Other studies have reported significant improvement in the symptoms of autistic children following treatment with chelating drugs that remove metals from the body. In a 2002 study, 10 patients with autism were treated with a chelating agent. All but two of the patients showed improvement in their ATEC scores (Lonsdale et al., Neuro Endocrinol Lett 2002, 23:303). A study in 2003 by Jeff Bradstreet compared mercury excretion after three day treatment using the chelating agent, DMSA, and found that children with autism excreted three times the amount of mercury in their urine as the non-autistic control group (Bradstreet, et al., J Am Phys Surg 2003, 8:76).
These are only a sampling of the groundbreaking studies by Egyptian scientists, doctors and researchers on the etiology of autism. Impressive Egyptian studies beg a host of questions for public health officials and American citizens. Most prominently: why can a chaotic society in a war torn and relatively impoverished nation produce high quality science on the etiology and successful treatments of autism while the science on the environmental triggers of autism in the U.S. is stagnant despite the National Institutes of Health spending more than $1 billion on autism research since 2010?
Last month, The Hill published a letter sent by "more than a dozen" senior Center for Disease Control (CDC) scientists charging the agency with nursing an atmosphere of pervasive research fraud.
The group, which claimed to represent scientists across the CDC's diverse branches, calls itself SPIDER (Scientists Preserving Integrity, Diligence and Ethics in Research). The letter to CDC Chief of Staff, Carmen Villar, expressed alarm "about the current state of ethics at our agency." The scientists complained that "our mission is being influenced and shaped by outside parties and rogue interests" and "circumvented by some of our leaders."
The scientists told Villar that, "questionable and unethical practices, occurring at all levels and in all of our respective units, threaten to undermine our credibility and reputation as a trusted leader in public health." The letter charged that staff level scientists "are intimidated and pressed to do things they know are not right," and that, "Senior management officials at CDC are clearly aware and even condone these behaviors."
The scientists cited several recent scandals involving scientific corruption at CDC.
The scientists complain that the "climate of disregard" at CDC puts "many" agency scientists in difficult positions. "We are often directed to do things we know are not right." The public record supports SPIDER's allegations that scientists who insist on research integrity suffer persecution by CDC supervisors.
The recent SPIDER letter highlights the culture of deep-rooted scientific corruption that has metastasized across CDC and become the subject of a decade- long parade of investigations.
Given this long history of deeply entrenched scientific chicanery at the CDC, it's no surprise that scientists are now complaining. If Donald Trump is sincere about his promise to "Drain the Swamp" in the federal bureaucracy, he should begin by appointing an honest and able CDC director who can restore transparency, credibility, robust science and regulatory independence at the agency and who will turn around the culture of corruption that has been so damaging to children's health.
Thomas Frieden, the director of the Center for Disease Control (CDC), has blocked CDC whistleblower, Dr. William Thompson, from testifying on scientific fraud and destruction of evidence by senior CDC officials in critical vaccine safety studies regarding the causative relationship between childhood vaccines and autism.
The medical malpractice case seeking Dr. Thompson's testimony is on behalf of 16-year-old Yates Hazlehurst. The lawsuit alleges that Yates is autistic as a result of vaccine injuries.
Attorneys Bryan Smith and Robert F. Kennedy, Jr., of Morgan & Morgan, have been seeking to have Dr. Thompson testify in a medical malpractice case to explain how the CDC committed scientific fraud in a series of studies, which found no link between vaccines and autism.
In denying the request, Dr. Frieden said, "Dr. William Thompson's deposition testimony would not substantially promote the objectives of CDC or HHS [Health and Human Services]."
Dr. Thompson, a 19-year veteran at the CDC and former senior vaccine safety scientist at the agency's Immunology Safety Office, is the co-author of four key studies that the CDC widely touts to exonerate the MMR vaccine and vaccines containing the mercury-based preservative thimerosal, from being linked to autism. Thompson is currently employed at the CDC's National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention.
In August 2014, Dr. Thompson revealed that the data underlying CDC's principle vaccine safety studies demonstrated a causal link between vaccines and autism or autism symptoms, despite CDC's claims to the contrary. According to Thompson, based upon interpretation of the data, "There is biologic plausibility right now to say that thimerosal causes autism-like features." Dr. Thompson invoked federal whistleblower protection in August 2014.
Dr. William Thompson is listed as author or co-author on the principal studies—Thompson, et al. 2007, Price, et al. 2010, Destefano, et al. 2004—most widely cited to "debunk" the link between autism and vaccines. Thompson said that his bosses, including the CDC's Immunization Safety Office Branch Chief Frank Destefano, specifically ordered him and three other CDC scientists to destroy data demonstrating vaccine induced autism in CDC's seminal 2004 study—Destefano, et al. 2004. The data unexpectedly showed a 250 percent increase in autism among young black males who received the vaccine on time—before their third birthday—compared to those who waited until after their third birthday. The data also showed a significant link between the vaccine and isolated autism (autism in normally developing children with no other medical problems), the kind suffered by Yates Hazlehurst, who is mentioned below. According to Thompson, Destefano called his four co-authors into a room and ordered them to dump the damning datasets into a giant garbage can. The published study omitted those data sets. That study, now cited in 91 subsequent papers on PubMed as proof of vaccine safety, is the principle foundation stone of the theology that vaccines don't cause autism.
In a series of taped statements, a deposition to Congressman William Posey of Florida and in statements issued through his personal attorney, Thompson confirmed that the data underlying the seminal 2004 Atlanta study, Destefano, et al. 2004, showed a causal association between MMR and autism for both African-American boys and for children suffering isolated autism. Thompson also asserted that CDC's leading thimerosal studies, rather than demonstrating thimerosal's safety, have consistently showed a causal relationship between thimerosal and tics, a family of grave neurological injuries that are a well-established feature of autism.
The medical malpractice case seeking Dr. Thompson's testimony is on behalf of 16-year-old Yates Hazlehurst. The lawsuit alleges that Yates is autistic as a result of vaccine injuries, which occurred when the vaccines were improperly administered in 2001. Because of the Vaccine Injury Compensation Act of 1986 (VICA), Hazlehurst v. The Jackson Clinic is the only vaccine injury case that has gone to any U.S. court in 30 years.
Under the VICA and the 2009 Supreme Court decision Bruesewitz v. Wyeth, almost all vaccine injured children are barred from filing lawsuits in state or federal courts. Instead, their only legal remedy is to seek compensation under VICA in the so called "vaccine court," the popular term which refers to the Office of Special Masters of the U.S. Court of Federal Claims, which administers a no-fault system for litigating vaccine injury claims. There is no judge, no jury and the most basic rules of law do not apply.
However, the U. S. Department of Health and Human Services subsequently admitted that during the Omnibus Autism Proceeding it secretly settled and sealed what potentially would have been one of the six test cases, Poling v. HHS after HHS conceded that the vaccines did indeed cause her autism. By conceding the Poling case and opposing the parents motion for complete transparency, HHS concealed critical evidence of how vaccines can cause autism.
Dr. Thompson wants to reveal the scientific fraud and destruction of evidence that took place in the studies that he co-authored. However, in accordance with the Whistle Blower Protection Act and other federal regulations, Dr. Thompson can not testify under oath without the permission of the director of the CDC, Dr. Thomas Frieden.
Hazlehurst's attorneys, Smith and Kennedy, sought the permission of the CDC to allow Dr. Thompson to testify. The request on behalf of Hazlehurst specifically relates to the issue of causation, i.e. the issue of whether vaccines can cause autism, which the State of Tennessee Circuit Court Judge found to be both relevant and a proper basis for seeking the deposition of Dr. Thompson.
According to Kennedy, who argued before Tennessee Senior Circuit Court Judge William Acree that Dr. Thompson's testimony was necessary, "Yates, and almost 5,000 other vaccine injured autistic children, lost their cases in vaccine court because CDC and the Justice Department submitted fraudulent science wrongly denying the vaccine-autism link."
Kennedy explained that Dr. Thompson's testimony was necessary to explain details of the fraud. "Dr. Thompson will also rebut defense experts' testimony that Yates was not damaged because vaccines do not cause autism," Kennedy said.
Accepting the logic of Kennedy's argument, Judge Acree ordered on Feb. 5 that Dr. Thompson should be deposed. Following Judge's Acree's ruling, Smith filed a formal request to CDC to make Thompson available for deposition and trial testimony.
On Sept. 22, in a letter from CDC Director Thomas Freiden, CDC denied Smith's request. Smith explained that "this denial was a disappointment but not a surprise, since the inescapable implication of Dr. Thompson's testimony is that the agency fraudulently altered the science to undermine autism cases worth potentially $1 trillion in compensation ordered by Congress."
Smith and Kennedy plan to immediately appeal the CDC's denial to federal court.
"Since that original study data is only available from Dr. Thompson," Smith explained, "We are very confident that a federal judge will order CDC to make Thompson available."
An international team of scientists led by the U.S Geological Survey (USGS) released a comprehensive report last week showing widespread mercury contamination across western North America.
The report, based on decades of mercury data and research, found alarming levels of mercury and methylmercury in the forests, fishes, wildlife, plants and waterways of America's western landscapes. The USGS study provides the first integrated analysis of where mercury occurs in western North America, how it moves through the environment, and the processes that influence its movement and transfer to aquatic and ultimately, the human food chain.
Fish are indicators of methylmercury contamination because they are an important link in the food chain for both wildlife and humans.U.S. Forest Service
Among the many disturbing findings are shocking accumulations of mercury in densely forested areas such as those found along the Pacific mountain ranges of California and Oregon. The scientific team showed that these critical ecosystems collect dangerous mercury loads because they receive high amounts of precipitation. Rainfall washes mercury from the atmosphere onto wet forested regions where it binds to the vegetation and accumulates in the soils and surface waters. From these vectors it can bioaccumulate in fish, including salmon.
Vegetation patterns affect both soil moisture and the amount of sunlight that reaches the soil, two factors associated with mercury release from soils.U.S. Fish and Wildlife Service
The report confirms the findings of a January 2016 study that narrowly investigated mercury levels in rainfall. That study reported that the long-term trend of decreasing mercury levels in precipitation had leveled off and that some sites in the western U.S. were experiencing increases, which the investigators concluded were due to exploding mercury emissions from Asia.
An earlier study in 2002 reported that industrial emissions in Asia are a major source of mercury in rainwater falling along the California coast. The new USGS study describes the precise atmospheric transport mechanisms that carry massive mercury contamination from Asia and deposit the potent neurotoxin in the water, soils and biota across America's West Coast. According to the papers lead author, it is not just the mercury itself, but a cocktail of atmospheric pollutants that contribute to the deposition of mercury in rainfall. Elemental mercury behaves as a gas in the atmosphere and is not washed out in rain until it has been oxidized into a charged ionic form that can be captured by water droplets.
The USGS study sheds light on earlier research with frightening human health implications. A 2008 study reported children living in areas of high precipitation may be more likely to have autism. Those investigators looked at rainfall in California, Washington and Oregon. That team obtained autism prevalence rates for children born in those three states between 1987 and 1999 and calculated average annual precipitation by county from 1987 to 2001. The researchers also computed the autism rates in relation to the average annual precipitation in the counties when the children were younger than 3 years old.
Those scientists found that counties that received relatively large amounts of precipitation had a relatively high rate of autism. More specifically, counties in Oregon and Washington west of the Cascades receive four times as much precipitation as counties east of the Cascades, and had an autism rate that was twice as high. These are the same states that were identified in the USGS's comprehensive report demonstrating the relationship between mercury deposition and precipitation.
The team also looked at each county over time, taking into account the varying annual precipitation levels. The study authors performed this analysis to rule out the effect of other factors, such as differences in the quality of the health care systems from one county to another. The relationship between precipitation and autism held.
Several earlier studies have established a potential connection between mercury from industrial air pollution and autism. In 2006 researchers in Texas reported that on average, for each 1,000 pounds of environmentally released mercury, there was a 43 percent increase in the rate of special education services and a 61 percent increase in the rate of autism. An investigation in the state of California found an association between autism and metal concentrations (mercury, cadmium, nickel, trichloroethylene) and possibly solvents (vinyl chloride).
These studies, however, concentrated on a few individual states. The latest study included women across the whole country. According to the first national study to investigate the possible link, living in an area with high levels of air pollution and mercury increased a woman's chances of having a child with autism.
"Women who were exposed to the highest levels of diesel or mercury in the air were twice as likely to have a child with autism than women who lived in the cleanest parts of the sample," according to the study author Andrea Roberts, a research associate with the Harvard School of Public Health.
Some researchers who first reported the correlation between high precipitation and high rates of autism, hypothesized that the link might be the result of children spending more time indoors where they generated less vitamin D or had increased exposures to household toxins. These reports gave little consideration to increased mercury exposure as a potential causative factor.
Key findings from the report include: