Scientists Are Freaking Out Over This 25-Year-Old's Solution to Superbugs
After three years of research, a Ph.D. student at the University of Melbourne may have discovered a way to kill superbugs without the use of antibiotics.
Shu Lam believes that she has found the key to averting a health crisis so severe that the United Nations recently declared it a "fundamental threat" to global health.
Antibiotic-resistant superbugs kill about 170,000 people a year and, according to a British study, are estimated to kill up to 10 million people a year by 2050 and cost the world economy $100 trillion.
"If we fail to address this problem quickly and comprehensively, antimicrobial resistance will make providing high-quality universal healthcare coverage more difficult if not impossible," UN Secretary General Ban Ki-moon told The Guardian. "It will undermine sustainable food production. And it will put the sustainable development goals in jeopardy."
In what is being hailed by scientists in the field as "a breakthrough that could change the face of modern medicine," Lam and her team developed a star-shaped peptide polymer that targets the resistant superbugs, rips apart their cell walls and kills them.
"These star polymers screw up the way bacteria survives," Lam told VICE. "Bacteria need to divide and grow but when our star is attached to the membrane it interferes with these processes. This puts a lot of stress on the bacteria and it initiates a process to kill itself from stress."
A bacterium cell before (left) and after being treated by the star-shaped polymers. University of Melbourne
Lam told The Telegraph the polymers have been effective in treating mice infected by antibiotic-resistant bacteria and are relatively non-toxic to the healthy cells in the body. The reduction in toxicity is because of the larger size of the polymers which make them too big to enter healthy cells.
Lam's findings were recently published in the Nature Microbiology journal and while the results are promising in the lab and on mice, she said there is still a long way to go.
"We still need to do a lot of studies and a lot of tests—for example, to see whether these polymers have any side effects on our bodies," she explained to Vice. "We need a lot of detailed assessments like that, [but] they could hopefully be implemented in the near future."
Professor Greg Qiao, her Ph.D. supervisor, told The Telegraph they will need at least five more years to fully develop her project unless millions of dollars are invested into speeding up the process.
However, "The really good news about this is that, at the moment, if you have a superbug and you run out of antibiotics, there's not much you can do. At least you can do something now," he said.
So what would the star polymer treatment look like in the future? As Lam explained in an interview with VICE:
"The quickest way to make this available to the public is through topical application, simply because you go through less procedures as opposed to ingesting these molecules into the body. So when you have a wound or a bacterial infection on the wound then you [generally] apply some sort of antibacterial cream.
"The star polymers could potentially become one of the anti-bacterial ingredients in this cream. Ultimately, we hope that what we're discovering here could replace antibiotics. In other words, we also hope that we will be able to inject this into the body to treat serious infections, or even to disperse it in the form of a pill which patients can take, just like somebody would take an antibiotic."
Santa Barbara Becomes First California City to Pass Resolution Against Offshore Oil and Gas Drilling
The Santa Barbara City Council approved a resolution Tuesday opposing new drilling off the California coast and fracking in existing offshore oil and gas wells. The resolution is the first in a new statewide campaign to rally local governments against proposals to expand offshore fossil fuel extraction in federal waters.
The vote—which makes Santa Barbara the first California city to oppose both fracking and new offshore drilling—follows President Trump's April 28 executive order urging federal agencies to expand oil and gas leasing in federal waters. The order could expose the Pacific Ocean to new oil leasing for the first time in more than 30 years.
Starting Wednesday, the vast majority of Americans can learn about every potentially harmful chemical in their drinking water and what scientists say are the safe levels of those contaminants. The Environmental Working Group's (EWG) new national Tap Water Database is the most complete source available on the quality of U.S. drinking water, aggregating and analyzing data from almost 50,000 public water systems in all 50 states and the District of Columbia.
The organization has earned a reputation for ambitious data-mining research projects that shake up policy debates and consumer markets. EWG's online Farm Subsidy Database, listing millions of subsidy recipients, and its Skin Deep guide to more than 70,000 personal care products, draw tens of millions of visitors every year.
By Stacy Malkan
Ever since they classified the world's most widely used herbicide as "probably carcinogenic to humans," a team of international scientists at the World Health Organization's (WHO) cancer research group have been under withering attack by the agrichemical industry and its surrogates.
In a front-page series, The Monsanto Papers, the French newspaper Le Monde described the attacks as "the pesticide giant's war on science," and reported, "to save glyphosate, the firm [Monsanto] undertook to harm the United Nations agency against cancer by all means."
The lengthy report from the Energy and Policy Institute uses reams of archival documents to demonstrate that utility industry representatives knew as far back as 1968 that burning fossil fuels could trigger "catastrophic effects" on the climate.
By Sharon Kelly
The Pennsylvania's Environmental Hearing Board ordered Sunoco Pipeline LP Tuesday to temporarily halt some types of work on a $2.5 billion pipeline project designed to carry 275,000 barrels a day of butane, propane and other liquid fossil fuels from Ohio and West Virginia, across Pennsylvania, to the Atlantic coast.
On July 19, three environmental groups presented Judge Bernard Labuskes, Jr. with documentation showing that the project had caused dozens of drilling fluid spills and other accidents between April and mid-June.
By Andy Rowell
The UK has followed France in banning the sale of new petrol and diesel cars by 2040, as part of its plan to tackle chronic air pollution in cities. The government has been coming under intense pressure to act, with an estimated 40,000 people dying prematurely a year from air pollution.
By Colleen Curry
People traveling across America today can, if they're lucky, pitch a tent in the same exact spot that early American explorers and map-makers Lewis and Clark did, amid the jagged rocks and sweeping plains of the Upper Missouri River Breaks in central Montana.
Brent Rose, a journalist and filmmaker who has been traveling around the U.S. in a van for two years, was one of the lucky ones.
Kyara, a killer whale born at SeaWorld San Antonio just three months ago, died Monday at the park, as reported in this video from Newsy. Kyara is the last orca to be born in captivity under the SeaWorld breeding program, which shut down in 2016.
In a statement, SeaWorld said the cause of death was "likely pneumonia" and that "Kyara had faced some very serious and progressive health issues over the last week."