Study Finds Hydroxychloroquine Has No Benefit for Treating COVID-19
The evidence against hydroxychloroquine as an effective treatment for COVID-19 is growing stronger. Last week, as EcoWatch reported, several studies around the world found an increased risk of heart complications when chloroquine or hydroxychloroquine was taken with azithromycin.
Now, a new study of hundreds of patients at U.S. Veterans Health Administration medical centers found that coronavirus patients taking hydroxychloroquine, with or without azithromycin, were no less likely to need mechanical ventilation. In fact, they even had higher deaths rates compared to those who did not take the drug, as CNN reported.
The study, which was funded by the National Institute of Health (NIH) and the University of Virginia, was posted Tuesday on medrxiv.org, a pre-print server that was not peer reviewed or published in a medical journal.
The evidence refutes Donald Trump's continued suggestions that the drug might be helpful in fighting COVID-19. On March 21, for example, Trump described the combination of hydroxychloroquine and azithromycin in a tweet as having a "real chance to be one of the biggest game changers in the history of medicine," as NPR reported.
To conduct the study, researchers analyzed medical records of 368 male veterans hospitalized with confirmed coronavirus infection who died or were discharged by April 11. About 28 percent who were given hydroxychloroquine plus usual care died. That is compared to 11 percent of those who only had routine care, according to the AP.
Nearly 22 percent of people getting the drug plus azithromycin died as well, but the difference between that group and usual care was not considered large enough to rule out other factors that could have complicated survival, according to the AP.
"An association of increased overall mortality was identified in patients treated with hydroxychloroquine alone. These findings highlight the importance of awaiting the results of ongoing prospective, randomized, controlled studies before widespread adoption of these drugs," wrote the authors, who work at the Columbia VA Health Care System in South Carolina, the University of South Carolina and the University of Virginia, as CNN reported.
Hydroxychloroquine also made no difference in the need for a breathing machine. Rates of mechanical ventilation were 13 percent for those who got the drug versus 14 percent for patients who received only supportive care, as Reuters reported.
"Some publications in the last week or two have shed doubt on whether hydroxychloroquine is beneficial," said Dr. Jeremy Falk, a pulmonary specialist at Cedars-Sinai Medical Center in Los Angeles, who was not involved in the VA study, to Reuters. "We were using it on just about everybody early on. Now we are using it more sparingly."
The mounting evidence prompted a panel of experts convened by the National Institute of Allergy and Infectious Diseases to recommend against doctors using a combination of hydroxychloroquine and azithromycin for the treatment of COVID-19 because of potential toxicities.
Dr. Anthony Fauci, who has maintained that novel approaches to treating COVID-19 need more evidence before they are recommended, leads the National Institute of Allergy and Infectious Diseases.
The recommendations were released on Tuesday. Notably, Fauci did not appear with Trump at the White House's Coronavirus Task Force press briefing. The president said he had not yet seen the new guidelines from Fauci's panel, according to The New York Times."It's all based on the data," said panel member Dr. Susan Swindells, a professor in the department of internal medicine at the University of Nebraska College of Medicine, as NPR reported. "We just plowed through everything that was, and apart from supportive care, there wasn't anything that was working terribly well."
- Drugs Touted by Trump for COVID-19 Increase Heart Risks, Studies ... ›
- FDA Issues Emergency Authorization to Treat COVID-19 With ... ›
- WHO Suspends Trial of Trump-Touted COVID-19 Treatment Hydroxychloroquine Due to Safety Concerns - EcoWatch ›
By Kate Whiting
From Greta Thunberg to Sir David Attenborough, the headline-grabbing climate change activists and environmentalists of today are predominantly white. But like many areas of society, those whose voices are heard most often are not necessarily representative of the whole.
1. Wangari Maathai<p>In 2004, Professor Maathai made history as the <a href="https://www.nobelpeaceprize.org/Prize-winners/Prizewinner-documentation/Wangari-Maathai" target="_blank" rel="noopener noreferrer">first African woman to be awarded the Nobel Peace Prize</a> for her dedication to sustainable development, democracy and peace. She started the <a href="http://www.greenbeltmovement.org/" target="_blank" rel="noopener noreferrer">Green Belt Movement</a>, a community-based tree planting initiative that aims to reduce poverty and encourage conservation, in 1977. More than 51 million trees have been planted helping build climate resilience and empower communities, especially women and girls. Her environmental work is celebrated every year on <a href="http://www.greenbeltmovement.org/node/955" target="_blank" rel="noopener noreferrer">Wangari Maathai Day on 3 March</a>.</p>
2. Robert Bullard<p>Known as the 'father of environmental justice,' Dr Bullard has <a href="https://www.unep.org/championsofearth/laureates/2020/robert-bullard" target="_blank">campaigned against harmful waste</a> being dumped in predominantly Black neighborhoods in the southern states of the U.S. since the 1970s. His first book, Dumping in Dixie, highlighted the link between systemic racism and environmental oppression, showing how the descendants of slaves were exposed to higher-than-average levels of pollutants. In 1994, his work led to the signing of the <a href="https://www.nrdc.org/experts/albert-huang/20th-anniversary-president-clintons-executive-order-12898-environmental-justice" target="_blank">Executive Order on Environmental Justice</a>, which the <a href="https://www.whitehouse.gov/briefing-room/presidential-actions/2021/01/27/executive-order-on-tackling-the-climate-crisis-at-home-and-abroad/" target="_blank">Biden administration is building on</a>.<br></p>
<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="7983f54726debdd824f97f9ad3bdbb87"><iframe lazy-loadable="true" src="https://www.youtube.com/embed/T_VjSGk8s18?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span>
Pollution has a race problem. Elizabethwarren.com
3. John Francis<p>Helping the clean-up operation after an oil spill in San Francisco Bay in January 1971 inspired Francis to <a href="https://planetwalk.org/about-john/" target="_blank" rel="noopener noreferrer">stop taking motorized transport</a>. Instead, for 22 years, he walked everywhere. He also took a vow of silence that lasted 17 years, so he could listen to others. He has walked the width of the U.S. and sailed and walked through South America, earning the nickname "Planetwalker," and raising awareness of how interconnected people are with the environment.</p>
<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="09b968e0e9964e31406954dcea45981d"><iframe lazy-loadable="true" src="https://www.youtube.com/embed/vgQjL23_FoU?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span>
4. Dr. Warren Washington<p>A meteorology and climate pioneer, Dr. Washington was one of the first people to develop atmospheric computer models in the 1960s, which have helped scientists understand climate change. These models now also incorporate the oceans and sea ice, surface water and vegetation. In 2007, the <a href="https://www.cgd.ucar.edu/pcm/" target="_blank" rel="noopener noreferrer">Parallel Climate Model (PCM)</a> and <a href="https://www.cesm.ucar.edu/" target="_blank" rel="noopener noreferrer">Community Earth System Model (CESM)</a>, earned Dr. Washington and his colleagues the <a href="https://www.nobelprize.org/prizes/peace/2007/summary/" target="_blank" rel="noopener noreferrer">Nobel Peace Prize</a>, as part of the <a href="https://www.ipcc.ch/" target="_blank" rel="noopener noreferrer">Intergovernmental Panel on Climate Change</a>.</p>
<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="09fbf6dc37f275f438a0d53ec0fe1874"><iframe lazy-loadable="true" src="https://www.youtube.com/embed/bvJ4jTy2mTk?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span>
5. Angelou Ezeilo<p>Huge trees and hikes to pick berries during her childhood in upstate New York inspired Ezeilo to become an environmentalist and set up the <a href="https://gyfoundation.org/staff/Angelou-Ezeilo" target="_blank" rel="noopener noreferrer">Greening Youth Foundation</a>, to educate future generations about the importance of preservation. Through its schools program and Youth Conservation Corps, the social enterprise provides access to nature to disadvantaged children and young people in the U.S. and West Africa. In 2019, Ezeilo published her book <em>Engage, Connect, Protect: Empowering Diverse Youth as Environmental Leaders</em>, co-written by her Pulitzer Prize-winning brother Nick Chiles.</p>
<span style="display:block;position:relative;padding-top:56.25%;" class="rm-shortcode" data-rm-shortcode-id="ce4547d4e5c0b9ad2927f19fd75bf4ab"><iframe lazy-loadable="true" src="https://www.youtube.com/embed/YojKMfUvJMs?rel=0" width="100%" height="auto" frameborder="0" scrolling="no" style="position:absolute;top:0;left:0;width:100%;height:100%;"></iframe></span>
- Youth Climate Activists Want a Role in Biden's White House ... ›
- As Protests Rage, Climate Activists Embrace Racial Justice ... ›
- The Power of Inclusive, Intergenerational Climate Activism - EcoWatch ›
EcoWatch Daily Newsletter
- Human Noise Pollution Is Harming Ocean Creatures - EcoWatch ›
- Mercury Pollution Found in Deepest Part of Ocean - EcoWatch ›
- Study: Plastic Pollution Increases Ocean Acidification - EcoWatch ›
The Postal Service is updating its massive fleet of mail carrying vehicles, heralding a significant step toward reducing carbon pollution from its massive fleet while also helping to protect its workforce from climate impacts.
- Texas Blackouts Reveal How Electric Vehicles Can Provide Power ... ›
- Ask a Scientist: Electric Vehicles are the Cleanest Option Today ... ›
After a second day of Senate hearings, Representative Deb Haaland (D-NM) is poised to become the first Native to serve as Secretary of the Interior (or any such high-ranking cabinet position.)
- Joe Biden Appoints Climate Crisis Team - EcoWatch ›
- Democrats Unveil Bill Addressing Cultural Genocide Against Native ... ›
- Biden Taps Rep. Deb Haaland to Lead Interior in Historic Move ... ›
A rare yellow penguin has been photographed for what is believed to be the first time.
- World-Renowned Photographer Documents Most Remote ... ›
- This Penguin Colony Has Fallen by 77% on Antarctic Islands ... ›