Government Fails to Protect American's from Superbug Epidemic
Let's talk about America's farmgrown terrorism epidemic. Back on Sept. 11, nearly 3,000 people lost their lives in the attacks on the World Trade Center, Pentagon, and in Shanksville, Pennsylvania. Since 9/11, our government has spent more than $7.6 trillion on military and homeland security operations in response to the deaths of those roughly 3,000 souls. Now, compare that to the fact that each year, 23,000 Americans die from antibiotic-resistant infections, and another 2 million get sick. That's the equivalent of nearly eight 9/11's per year. But our government isn't doing a thing about it.
In 2011 alone, nearly 30 million pounds of antibiotics were purchased by Big Agriculture, to promote growth in the animals, and to reduce the spread of disease in the horrific factory farm conditions. Photo credit: Shutterstock
Each year, Big Agriculture feeds millions and millions of pounds of antibiotics to factory farm animals, all to slightly increase their profits by plumping up their meat. In 2011 alone, nearly 30 million pounds of antibiotics were purchased by Big Agriculture, to promote growth in the animals, and to reduce the spread of disease in the horrific factory farm conditions. That 30 million pounds is a staggering four times the amount of antibiotics that were prescribed to humans that year.
These are otherwise healthy animals, but they're getting dosed daily with low levels of antibiotics anyway. As a result, this widespread and unnecessary use of antibiotics in factoryfarm animals is creating a major public health crisis here in the U.S by breeding antibiotic resistant infections caused by bacteria referred to in the media as superbugs.
But rather then enforcing regulations already in place to control the use of antibiotics in factory farm animals, our federal government is bowing to the interests of Big Agriculture, and is continuing to let the abuse go on.
Just last week, the U.S. Second Circuit Court of Appeals ruled that the Food and Drug Administration could leave an antibiotic that's used in animal feed on the market, even though the dangers associated with that antibiotic are widely known, including the increased risk of antibiotic resistance infections jumping to human beings. Basically, the court gave Big Agriculture the goahead to continue pumping millions and millions of pounds of antibiotics into poultry and livestock, with no concern for public safety.
So, why should Americans care about this? Well, for starters, Americans eat a lot of meat. And the superbugs and antibioticresistant bacteria that are bred on factory farms very easily make their way into our food system.
For example, last year, a drugresistant salmonella outbreak tied to chicken from Foster Farms sickened more than 600 Americans, and that outbreak is still getting worse today. And if that wasn't bad enough, these antibioticresistant superbugs also get into our water supply, and into soil for crops. The situation is so dire that, speaking about antibiotic resistance, Dr. Thomas Freidman, director of the Centers for Disease Control, said that, "If we don't act now, our medicine cabinet will be empty and we won't have the antibiotics we need to save lives."
If 23,000 Americans are already dying from superbugs and antibioticresistant infections each year, just imagine how much worse it could get as this antibiotic abuse continues. We could soon have a fullblown pandemic on our hands. But it doesn't have to get worse. We can stop this farmgrown terrorism right now, andsave millions of lives.
Big Agriculture says that slashing its use of antibiotics will hurt all of us in the form of higher prices at the supermarket, but that's simply not the case. As Ruth Reichl points out over at The New York Times, "Although many industrial farmers claim that cleaning up their act will cost the rest of us at the cash register, responsible producers from Missouri to Denmark are already raising healthy livestock and poultry at competitive prices without the use of unnecessary drugs."
Reichl highlights the story of Russ Kremer, a fifthgeneration pork farm in Missouri, who, after nearly being killed by an antibioticresistant infection on his own farm, decided to do things the all natural way. He lets his pigs roam free, and doesn't have to stuff them full of antibiotics, because they're not living in squalor. And, thanks to competitive prices, his meat is bought by companies like Chipotle and Costco.
So Big Agriculture's "higher meat prices" argument is complete bologna. Pun intended. The use of antibiotics on factory farms is all about profits for Big Agriculture, But, with 23,000 Americans dying each year as a result, it's time to start putting the American people ahead of profits.
Meat producers and sellers across the country need to say "no" to more superbugs. No animals on factory farms should ever be given antibiotics, unless diagnosed as sick by a veterinarian. And while we're at it, we need to work harder to close down Washington's revolving door, which encourages employees in government agencies like the FDA to get bought off by corporate interests and then turn a blind eye to corporate abuse.
We have a right to eat food that's not going to kill us.
You Might Also Like
In 2010, world leaders agreed to 20 targets to protect Earth's biodiversity over the next decade. By 2020, none of them had been met. Now, the question is whether the world can do any better once new targets are set during the meeting of the UN Convention on Biodiversity in Kunming, China later this year.
- Ocean Scientists Create Global Network to Help Save Biodiversity ... ›
- 5 Reasons Why Biodiversity Matters - EcoWatch ›
- 26 Organizations Working to Conserve Seed Biodiversity - EcoWatch ›
- The Top 10 Ocean Biodiversity Hotspots to Protect - EcoWatch ›
- New Platform Shows How to Protect Biodiversity and Save Planet ... ›
- These Scientists Are Listening to the Borneo Rainforest to Protect ... ›
EcoWatch Daily Newsletter
By Andrew Rosenberg
The first 24 hours of the administration of President Joe Biden were filled not only with ceremony, but also with real action. Executive orders and other directives were quickly signed. More actions have followed. All consequential. Many provide a basis for not just undoing actions of the previous administration, but also making real advances in public policy to protect public health, safety, and the environment.
- Here Are Biden's Day One Actions on Climate and Environment ... ›
- UCS Offers Science Advice for Biden Administration - EcoWatch ›
A first-of-its-kind study has examined the satellite record to see how the climate crisis is impacting all of the planet's ice.
- 'Ghost Forests' Are an Eerie Sign of Sea-Level Rise - EcoWatch ›
- Sea-Level Rise Takes Business Toll in North Carolina's Outer Banks ... ›
- Sea Level Rise Is Locked in Even If We Meet Paris Agreement ... ›
By Ana Maldonado-Contreras
- Your gut is home to trillions of bacteria that are vital for keeping you healthy.
- Some of these microbes help to regulate the immune system.
- New research, which has not yet been peer-reviewed, shows the presence of certain bacteria in the gut may reveal which people are more vulnerable to a more severe case of COVID-19.
You may not know it, but you have an army of microbes living inside of you that are essential for fighting off threats, including the virus that causes COVID-19.
How Do Resident Bacteria Keep You Healthy?<p>Our immune defense is part of a complex biological response against harmful pathogens, such as viruses or bacteria. However, because our bodies are inhabited by trillions of mostly beneficial bacteria, virus and fungi, activation of our immune response is tightly regulated to distinguish between harmful and helpful microbes.</p><p>Our bacteria are spectacular companions diligently helping prime our immune system defenses to combat infections. A seminal study found that mice treated with antibiotics that eliminate bacteria in the gut exhibited an impaired immune response. These animals had low counts of virus-fighting white blood cells, weak antibody responses and poor production of a protein that is vital for <a href="https://doi.org/10.1073/pnas.1019378108" target="_blank">combating viral infection and modulating the immune response</a>.</p><p><a href="https://doi.org/10.1371/journal.pone.0184976" target="_blank" rel="noopener noreferrer">In another study</a>, mice were fed <em>Lactobacillus</em> bacteria, commonly used as probiotic in fermented food. These microbes reduced the severity of influenza infection. The <em>Lactobacillus</em>-treated mice did not lose weight and had only mild lung damage compared with untreated mice. Similarly, others have found that treatment of mice with <em>Lactobacillus</em> protects against different <a href="https://doi.org/10.1038/srep04638" target="_blank" rel="noopener noreferrer">subtypes of</a> <a href="https://doi.org/10.1038/s41598-017-17487-8" target="_blank" rel="noopener noreferrer">influenza</a> <a href="https://doi.org/10.1371/journal.ppat.1008072" target="_blank" rel="noopener noreferrer">virus</a> and human respiratory syncytial virus – the <a href="https://doi.org/10.1038/s41598-019-39602-7" target="_blank" rel="noopener noreferrer">major cause of viral bronchiolitis and pneumonia in children</a>.</p>
Chronic Disease and Microbes<p>Patients with chronic illnesses including Type 2 diabetes, obesity and cardiovascular disease exhibit a hyperactive immune system that fails to recognize a harmless stimulus and is linked to an altered gut microbiome.</p><p>In these chronic diseases, the gut microbiome lacks bacteria that activate <a href="https://doi.org/10.1126/science.1198469" target="_blank" rel="noopener noreferrer">immune cells</a> that block the response against harmless bacteria in our guts. Such alteration of the gut microbiome is also observed in <a href="https://doi.org/10.1073/pnas.1002601107" target="_blank" rel="noopener noreferrer">babies delivered by cesarean section</a>, individuals consuming a poor <a href="https://doi.org/10.1038/nature12820" target="_blank" rel="noopener noreferrer">diet</a> and the <a href="https://doi.org/10.1038/nature11053" target="_blank" rel="noopener noreferrer">elderly</a>.</p><p>In the U.S., 117 million individuals – about half the adult population – <a href="https://health.gov/our-work/food-nutrition/2015-2020-dietary-guidelines/guidelines/" target="_blank" rel="noopener noreferrer">suffer from Type 2 diabetes, obesity, cardiovascular disease or a combination of them</a>. That suggests that half of American adults carry a faulty microbiome army.</p><p>Research in my laboratory focuses on identifying gut bacteria that are critical for creating a balanced immune system, which fights life-threatening bacterial and viral infections, while tolerating the beneficial bacteria in and on us.</p><p>Given that diet affects the diversity of bacteria in the gut, <a href="https://www.umassmed.edu/nutrition/melody-trial-info/" target="_blank" rel="noopener noreferrer">my lab studies show how diet can be used</a> as a therapy for chronic diseases. Using different foods, people can shift their gut microbiome to one that boosts a healthy immune response.</p><p>A fraction of patients infected with SARS-CoV-2, the virus that causes COVID-19 disease, develop severe complications that require hospitalization in intensive care units. What do many of those patients have in common? <a href="https://www.cdc.gov/mmwr/volumes/69/wr/mm6912e2.htm" target="_blank" rel="noopener noreferrer">Old age</a> and chronic diet-related diseases like obesity, Type 2 diabetes and cardiovascular disease.</p><p><a href="http://doi.org/10.1016/j.jada.2008.12.019" target="_blank" rel="noopener noreferrer">Black and Latinx people are disproportionately affected by obesity, Type 2 diabetes and cardiovascular disease</a>, all of which are linked to poor nutrition. Thus, it is not a coincidence that <a href="https://www.cdc.gov/mmwr/volumes/69/wr/mm6933e1.htm" target="_blank" rel="noopener noreferrer">these groups have suffered more deaths from COVID-19</a> compared with whites. This is the case not only in the U.S. but also <a href="https://www.washingtonpost.com/world/europe/blacks-in-britain-are-four-times-as-likely-to-die-of-coronavirus-as-whites-data-show/2020/05/07/2dc76710-9067-11ea-9322-a29e75effc93_story.html" target="_blank" rel="noopener noreferrer">in Britain</a>.</p>
Discovering Microbes That Predict COVID-19 Severity<p>The COVID-19 pandemic has inspired me to shift my research and explore the role of the gut microbiome in the overly aggressive immune response against SARS-CoV-2 infection.</p><p>My colleagues and I have hypothesized that critically ill SARS-CoV-2 patients with conditions like obesity, Type 2 diabetes and cardiovascular disease exhibit an altered gut microbiome that aggravates <a href="https://theconversation.com/exercise-may-help-reduce-risk-of-deadly-covid-19-complication-ards-136922" target="_blank" rel="noopener noreferrer">acute respiratory distress syndrome</a>.</p><p>Acute respiratory distress syndrome, a life-threatening lung injury, in SARS-CoV-2 patients is thought to develop from a <a href="http://doi.org/10.1016/j.cytogfr.2020.05.003" target="_blank" rel="noopener noreferrer">fatal overreaction of the immune response</a> called a <a href="https://theconversation.com/blocking-the-deadly-cytokine-storm-is-a-vital-weapon-for-treating-covid-19-137690" target="_blank" rel="noopener noreferrer">cytokine storm</a> <a href="http://doi.org/10.1016/S2213-2600(20)30216-2" target="_blank" rel="noopener noreferrer">that causes an uncontrolled flood</a> <a href="http://doi.org/10.1016/S2213-2600(20)30216-2" target="_blank" rel="noopener noreferrer">of immune cells into the lungs</a>. In these patients, their own uncontrolled inflammatory immune response, rather than the virus itself, causes the <a href="http://doi.org/10.1007/s00134-020-05991-x" target="_blank" rel="noopener noreferrer">severe lung injury and multiorgan failures</a> that lead to death.</p><p>Several studies <a href="https://doi.org/10.1016/j.trsl.2020.08.004" target="_blank" rel="noopener noreferrer">described in one recent review</a> have identified an altered gut microbiome in patients with COVID-19. However, identification of specific bacteria within the microbiome that could predict COVID-19 severity is lacking.</p><p>To address this question, my colleagues and I recruited COVID-19 hospitalized patients with severe and moderate symptoms. We collected stool and saliva samples to determine whether bacteria within the gut and oral microbiome could predict COVID-19 severity. The identification of microbiome markers that can predict the clinical outcomes of COVID-19 disease is key to help prioritize patients needing urgent treatment.</p><p><a href="https://doi.org/10.1101/2021.01.05.20249061" target="_blank" rel="noopener noreferrer">We demonstrated</a>, in a paper which has not yet been peer reviewed, that the composition of the gut microbiome is the strongest predictor of COVID-19 severity compared to patient's clinical characteristics commonly used to do so. Specifically, we identified that the presence of a bacterium in the stool – called <em>Enterococcus faecalis</em>– was a robust predictor of COVID-19 severity. Not surprisingly, <em>Enterococcus faecalis</em> has been associated with <a href="https://doi.org/10.1053/j.gastro.2011.05.035" target="_blank" rel="noopener noreferrer">chronic</a> <a href="https://doi.org/10.1016/S0002-9440(10)61172-8" target="_blank" rel="noopener noreferrer">inflammation</a>.</p><p><em>Enterococcus faecalis</em> collected from feces can be grown outside of the body in clinical laboratories. Thus, an <em>E. faecalis</em> test might be a cost-effective, rapid and relatively easy way to identify patients who are likely to require more supportive care and therapeutic interventions to improve their chances of survival.</p><p>But it is not yet clear from our research what is the contribution of the altered microbiome in the immune response to SARS-CoV-2 infection. A recent study has shown that <a href="https://doi.org/10.1101/2020.12.11.416180" target="_blank" rel="noopener noreferrer">SARS-CoV-2 infection triggers an imbalance in immune cells</a> called <a href="https://doi.org/10.1111/imr.12170" target="_blank" rel="noopener noreferrer">T regulatory cells that are critical to immune balance</a>.</p><p>Bacteria from the gut microbiome are responsible for the <a href="https://doi.org/10.7554/eLife.30916.001" target="_blank" rel="noopener noreferrer">proper activation</a> <a href="https://doi.org/10.1126/science.1198469" target="_blank" rel="noopener noreferrer">of those T-regulatory</a> <a href="https://doi.org/10.1038/nri.2016.36" target="_blank" rel="noopener noreferrer">cells</a>. Thus, researchers like me need to take repeated patient stool, saliva and blood samples over a longer time frame to learn how the altered microbiome observed in COVID-19 patients can modulate COVID-19 disease severity, perhaps by altering the development of the T-regulatory cells.</p><p>As a Latina scientist investigating interactions between diet, microbiome and immunity, I must stress the importance of better policies to improve access to healthy foods, which lead to a healthier microbiome. It is also important to design culturally sensitive dietary interventions for Black and Latinx communities. While a good-quality diet might not prevent SARS-CoV-2 infection, it can treat the underlying conditions related to its severity.</p><p><em><a href="https://theconversation.com/profiles/ana-maldonado-contreras-1152969" target="_blank">Ana Maldonado-Contreras</a> is an assistant professor of Microbiology and Physiological Systems at the University of Massachusetts Medical School.</em></p><p><em>Disclosure statement: Ana Maldonado-Contreras receives funding from The Helmsley Charitable Trust and her work has been supported by the American Gastroenterological Association. She received The Charles A. King Trust Postdoctoral Research Fellowship. She is also member of the Diversity Committee of the American Gastroenterological Association.</em></p><p><em style="">Reposted with permission from <a href="https://theconversation.com/a-healthy-microbiome-builds-a-strong-immune-system-that-could-help-defeat-covid-19-145668" target="_blank" rel="noopener noreferrer" style="">The Conversation</a>. </em></p>
By Jeff Masters, Ph.D.
The New Climate War: the fight to take back our planet is the latest must-read book by leading climate change scientist and communicator Michael Mann of Penn State University.
- 12 New Books Explore Fresh Approaches to Act on Climate Change ... ›
- Dr. Michael Mann on Climate Denial: 'It's Impaired Our Ability to ... ›