Quantcast
Health
Mike Mozart / Flickr / CC BY 2.0

NTP Scientist: Glyphosate Formulations 'Much More Toxic' Than Chemical Itself

Amid conflicting scientific studies and growing public concern over the impacts of the world's most widely used herbicide, the U.S. National Toxicology Program (NTP) has launched research to examine the health risks of glyphosate and glyphosate-formulations.

"Due to the multiple interpretations of evidence on the potential health risks of glyphosate exposure, major public concern about exposure risks, and reported differences in the toxicity of different glyphosate products, NTP is conducting more research on glyphosate and its formulations," according to the NTP website.


The NTP's initiative was first reported by Carey Gilliam in The Guardian. Gilliam is an author, investigative journalist and research director for U.S. Right to Know.

Glyphosate, the star ingredient in Monsanto's Roundup, is sprayed on agricultural fields around the world and helps beat back weeds in home gardens, golf courses and parks.

Gilliam noted, "Monsanto introduced its glyphosate-based Roundup brand in 1974. But it is only now, after more than 40 years of widespread use, that the government is investigating the toxicity of 'glyphosate-based herbicides' on human cells."

Jennifer Sass, a scientist with the Natural Resources Defense Council, commented to The Guardian, "This testing is important, because the EPA has only been looking at the active ingredient. But it's the formulations that people are exposed to on their lawns and gardens, where they play and in their food."

Glyphosate has been surrounded with controversy ever since March 2015, when the International Agency for Research on Cancer (IARC) classified the chemical as "probably carcinogenic to humans." The panel also concluded that there was "strong" evidence for genotoxicity both for "pure" glyphosate and for glyphosate formulations.

Later that year, the European Food Safety Authority's (EFSA) released its own report that rejected the IARC's classification of glyphosate as a possible carcinogen, but admitted that conclusion was just for the chemical alone.

EFSA's report stated: "The genotoxic effects observed in some glyphosate-based formulations are related to the other constituents or 'co-formulants.'"

According to a poster of the NTP's research, glyphosate formulations decreased human cell "viability" by disrupting cell membranes. Also, the concoctions "significantly altered" cell viability. (The poster does not necessarily represent any final NTP determination or policy.)

"We see the formulations are much more toxic. The formulations were killing the cells," Mike DeVito, acting chief of the National Toxicology Program Laboratory, told The Guardian. "The glyphosate really didn't do it."

Here are the specific aims of NTP:

  • Evaluate whether glyphosate is genotoxic (causes DNA damage)
  • Evaluate whether glyphosate induces oxidative damage
  • Compare the effects of glyphosate on measures of genotoxicity, oxidative stress, and cell viability to the effects of glyphosate-based formulations
  • Identify data gaps on the effects of glyphosate and glyphosate-based formulations on human health outcomes other than cancer.

Monsanto has adamantly defended the safety of its product. The U.S. Environmental Protection Agency also says that glyphosate is not likely to be carcinogenic to humans.

Other governments have taken action on such formulations. In 2016, the European Union banned glyphosate products mixed with the adjuvant POE-tallowamine due to its perceived risks to human health.

Tallowamine, which aids the effectiveness of glyphosate, was once found in Monsanto's Roundup. The inert ingredient was found to be "more deadly to human embryonic, placental and umbilical cord cells than [glyphosate] itself," Scientific American reported in 2009, citing a French study.

Show Comments ()
Sponsored
Health
Mark Doliner / CC BY-SA 2.0

110 Million Americans May Be Drinking PFAS-Contaminated Water

More than 1,500 drinking water systems across the country may be contaminated with the nonstick chemicals PFOA and PFOS, and similar fluorine-based chemicals, a new EWG analysis shows. This groundbreaking finding comes the same day the U.S. Environmental Protection Agency (EPA) is convening a summit to address PFAS chemicals—a class of toxic chemicals that includes PFOA and PFOS, and that are linked to cancer, thyroid disease, weakened immunity and other health problems.

Keep reading... Show less
Energy
Fern MacDougal's stand on Pocahontas Road. Appalachians Against Pipelines

Tree-Sitters Launch 9th Aerial Blockade of Mountain Valley Pipeline

Resistance is growing against the controversial Mountain Valley Pipeline (MVP) designed to carry fracked gas 300 miles from northwest West Virginia to southern Virginia.

On Monday morning, a woman named Fern MacDougal strung up a platform 30 feet in the air that is suspended by ropes tied to surrounding trees in Virginia's Jefferson National Forest.

Keep reading... Show less
Food
The Mediterranean diet emphasizes fruits, vegetables, whole grains and olive oil. G.steph.rocket / CC BY-SA 4.0

Can the Mediterranean Diet Protect You Against Air Pollution Health Risks?

Air pollution is a serious and growing public health concern. Ninety-five percent of the Earth's population breathes unsafe air, and scientists are discovering more and more health risks associated with doing so.

Keep reading... Show less
Climate
Increased ocean temperatures are causing Noctiluca scintillans to cause waves like these, photographed on a Japanese beach in 2017, to wash up on beaches in Mumbai. Doricono / CC BY-SA 4.0

Mumbai’s Glowing Waves a Sign of Climate Change

A recent study by Indian and U.S. scientists found that climate change might be the cause of an eerily beautiful phenomenon on Mumbai beaches, The Washington Post reported Monday.

Keep reading... Show less
Sponsored
Popular
Irma Omerhodzic

EPA Guard Shoves Reporter, Multiple News Outlets Blocked From Water Pollution Event

By Jessica Corbett

The U.S. Environmental Protection Agency (EPA) blocked reporters from CNN, E&E News and the Associated Press from attending a summit about water pollution on Tuesday, and a security guard reportedly grabbed a journalist by the shoulders and "forcibly" shoved her out of the building.

Keep reading... Show less
Climate
Simulated flooding caused by a Category 3 hurricane striking Theodore Roosevelt Island in Washington, DC. NPS

National Park Service Releases Climate Report That Officials Tried to Censor

The National Parks Service (NPS) quietly released a long-delayed report that mentions humanity's role in climate change, which officials had removed in earlier drafts.

The report, published Friday without a press release or any social media activity from the parks department or Interior Secretary Ryan Zinke, shows estimates of sea level change for 118 coastal national park sites and estimates of storm surge for 79 of the sites.

Keep reading... Show less
Sponsored
Climate
The Murphy oil site in West Adams, LA, sits as close as 200 feet from homes and playgrounds. Sarah Craig / Faces of Fracking / CC BY-NC-ND 2.0

Will Gov. Brown Plug the Dangerous Hole in California’s Climate Action?

By Kelly Trout

California Gov. Jerry Brown is gearing up to host leaders from state, tribal, and local governments, business and citizens from around the world at a Global Climate Action Summit in San Francisco this September. His goal is to "inspire deeper commitments" in support of the Paris agreement goals. He has emphasized that, on climate, "so far the response is not adequate to the challenge" and "no nation or state is doing what they should be doing."

Keep reading... Show less
Business
Alaska Airlines

Alaska Airlines Launches #StrawlessSkies Campaign

As part of its worldwide push "For a Strawless Ocean," Alaska Airlines announced Monday that its 44 million yearly passengers will fly in "strawless skies."

Starting July 16, the leading U.S. airline on the 2017 Dow Jones Sustainability Index will stop distributing single-use plastic stirring straws and citrus picks in its lounges and on its domestic and international flights. It is the the first U.S. airline to do so. The non-recyclable items, which the airline distributed 22 million of last year, will be replaced with Forest Stewardship Council certified birch stirring sticks and bamboo citrus pickers.

Keep reading... Show less
Sponsored

mail-copy

The best of EcoWatch, right in your inbox. Sign up for our email newsletter!