NTP Scientist: Glyphosate Formulations 'Much More Toxic' Than Chemical Itself
Amid conflicting scientific studies and growing public concern over the impacts of the world's most widely used herbicide, the U.S. National Toxicology Program (NTP) has launched research to examine the health risks of glyphosate and glyphosate-formulations.
"Due to the multiple interpretations of evidence on the potential health risks of glyphosate exposure, major public concern about exposure risks, and reported differences in the toxicity of different glyphosate products, NTP is conducting more research on glyphosate and its formulations," according to the NTP website.
Glyphosate, the star ingredient in Monsanto's Roundup, is sprayed on agricultural fields around the world and helps beat back weeds in home gardens, golf courses and parks.
Gilliam noted, "Monsanto introduced its glyphosate-based Roundup brand in 1974. But it is only now, after more than 40 years of widespread use, that the government is investigating the toxicity of 'glyphosate-based herbicides' on human cells."
Jennifer Sass, a scientist with the Natural Resources Defense Council, commented to The Guardian, "This testing is important, because the EPA has only been looking at the active ingredient. But it's the formulations that people are exposed to on their lawns and gardens, where they play and in their food."
Glyphosate has been surrounded with controversy ever since March 2015, when the International Agency for Research on Cancer (IARC) classified the chemical as "probably carcinogenic to humans." The panel also concluded that there was "strong" evidence for genotoxicity both for "pure" glyphosate and for glyphosate formulations.
Later that year, the European Food Safety Authority's (EFSA) released its own report that rejected the IARC's classification of glyphosate as a possible carcinogen, but admitted that conclusion was just for the chemical alone.
EFSA's report stated: "The genotoxic effects observed in some glyphosate-based formulations are related to the other constituents or 'co-formulants.'"
According to a poster of the NTP's research, glyphosate formulations decreased human cell "viability" by disrupting cell membranes. Also, the concoctions "significantly altered" cell viability. (The poster does not necessarily represent any final NTP determination or policy.)
"We see the formulations are much more toxic. The formulations were killing the cells," Mike DeVito, acting chief of the National Toxicology Program Laboratory, told The Guardian. "The glyphosate really didn't do it."
Here are the specific aims of NTP:
- Evaluate whether glyphosate is genotoxic (causes DNA damage)
- Evaluate whether glyphosate induces oxidative damage
- Compare the effects of glyphosate on measures of genotoxicity, oxidative stress, and cell viability to the effects of glyphosate-based formulations
- Identify data gaps on the effects of glyphosate and glyphosate-based formulations on human health outcomes other than cancer.
Monsanto has adamantly defended the safety of its product. The U.S. Environmental Protection Agency also says that glyphosate is not likely to be carcinogenic to humans.
Other governments have taken action on such formulations. In 2016, the European Union banned glyphosate products mixed with the adjuvant POE-tallowamine due to its perceived risks to human health.
Tallowamine, which aids the effectiveness of glyphosate, was once found in Monsanto's Roundup. The inert ingredient was found to be "more deadly to human embryonic, placental and umbilical cord cells than [glyphosate] itself," Scientific American reported in 2009, citing a French study.
French Ecology Minister Calls for Ban on #Glyphosate Formulations https://t.co/SjyDTIhsvr #Monsanto @nongmoreport https://t.co/WdOqMru4vC— EcoWatch (@EcoWatch)1455651663.0
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By Kristen Fischer
It's going to be back-to-school time soon, but will children go into the classrooms?
The American Academy of Pediatrics (AAP) thinks so, but only as long as safety measures are in place.
Keeping Schools Safe<p>What will safer schools look like?</p><p>In a <a href="https://jamanetwork.com/journals/jama/fullarticle/2766822" target="_blank">JAMA article</a> published last month, <a href="https://www.jhsph.edu/faculty/directory/profile/1781/joshua-m-sharfstein" target="_blank">Dr. Joshua Sharfstein</a>, a pediatrician and professor at the Johns Hopkins Bloomberg School of Public Health, outlined suggestions — many of which are similar to AAP's.</p><p>Remote learning protocols must stay in place, especially as some schools stagger home and in-building learning. If another shutdown needs to occur, children will rely on distance learning completely, so it must be easy to switch to, he said.</p><p>He suggested giving parents a daily checklist to document their child's health. Kids should be screened quickly on arrival and be given hygiene supplies. Maintenance staff should use appropriate PPE and have regular cleaning schedules. A notification system should be in place if a case is identified, Sharfstein recommended.</p><p><a href="https://www.albany.edu/rockefeller/faculty/erika-martin" target="_blank">Erika Martin</a>, PhD, an associate professor of public administration and policy at University at Albany, said nutrition assistance and health services should be included. She called for tutoring programs with virtual options as well as technology access.</p>
Supporting Staff<p>Teachers and staff will be affected by safeguarding measures, noted <a href="https://directory.sph.umn.edu/bio/sph-a-z/rachel-widome" target="_blank">Rachel Widome</a>, PhD, an associate professor of epidemiology and community health at University of Minnesota.</p><p>"In order for all of the in-school precautions to work well, we'll be asking a lot of teachers and staff," Widome told Healthline. In addition to their usual workload, they'll now be asked to monitor mask-wearing, ensure children are keeping distance, and be aware of any symptoms.</p><p>Along with Sharfstein, Widome called for an increase in financial support. More employees will likely be required so teachers and staff members can keep up with the added demands.</p>
Should Kids Go Back?<p>While these guidelines may help get some schools to reopen, many people don't think children should go back to school over fears they could contract the disease and spread it to other vulnerable family members like grandparents, infant siblings, or their parents.</p><p>In a <a href="https://pediatrics.aappublications.org/content/early/2020/07/08/peds.2020-004879" target="_blank">Pediatrics</a> commentary, <a href="https://www.md.com/doctor/william-raszka-md" target="_blank">Dr. William V. Raszka, Jr.</a>, an infectious disease specialist at The University of Vermont Medical Center, argued that schools should open because school-aged children are far less important drivers of COVID-19 than adults.</p><p>But he says the risk and benefit is not equal among all students ages 5 to 18.</p><p>"Elementary schools are arguably higher priority for face-to-face schooling, since younger children are at lower risk for infection and transmission, and since parental supervision of younger children's distance learning may be particularly challenging," added Sorensen, who penned a <a href="https://jamanetwork.com/channels/health-forum/fullarticle/2767411" target="_blank">June article in JAMA</a> with reopening tips. "That means middle and high schools are more likely to emphasize distance learning."</p><p>Specific student populations, such as special education students and students with disabilities, would also benefit greatly from more time spent in face-to-face environments, Sorensen said.</p>
What Parents Can Do<p>Parents should ask for and receive frequent updates from schools about plans for the fall. They should also be informed about plans if and when COVID infections are identified, Sharfstein said.</p><p>"I'd like to see parents investing now, during the summer, in doing things that can slow and stop the spread of the virus in their communities," Widome said.</p><p>"Now is a good time for kids to practice wearing masks and get used to them as they may be wearing them for longer stretches if school starts up in person," Widome suggested.</p><p>She recommends parents try different mask designs and materials to see what children are more comfortable wearing.</p><p>"If you are using cloth face coverings, it's good to have extras on hand," Widome added.</p><p>Parents should model healthy behavior at home and while out in public — another thing that could affect how well children adapt to reopening practices, Sorensen said.</p><p>"Children may want to know more about face coverings," added <a href="https://www.linkedin.com/in/leescott/" target="_blank">Lee Scott</a>, chairwoman of the Educational Advisory Board at <a href="https://www.goddardschool.com/" target="_blank">The Goddard School</a>. "Dramatic play, such as creating or wearing a face covering, may help some children adjust to this concept." Schools can also show children photos of what faculty members look like in their masks so the students are familiar with that appearance.</p><p>Johns Hopkins University recently released its eSchool+ Initiative, a slew of resources surrounding education during the pandemic. These include a <a href="https://equityschoolplus.jhu.edu/reopening-checklist/" target="_blank">checklist for administrators</a>, report on <a href="https://equityschoolplus.jhu.edu/ethics-of-reopening/" target="_blank">ethical considerations</a>, and a tracker of <a href="https://equityschoolplus.jhu.edu/reopening-policy-tracker/" target="_blank">state and local reopening plans</a>.</p>
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<div id="fea63" class="rm-shortcode" data-rm-shortcode-id="9a6f211c2bc5aedd34837944cb8eeedf"><blockquote class="twitter-tweet twitter-custom-tweet" data-twitter-tweet-id="1281000111481294849" data-partner="rebelmouse"><div style="margin:1em 0">Water in Illinois is overwhelmingly public. Why is Tammy Duckworth sponsoring a bill that aims to change that? https://t.co/1V36Kkd99s</div> — The American Prospect (@The American Prospect)<a href="https://twitter.com/TheProspect/statuses/1281000111481294849">1594249201.0</a></blockquote></div>
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