Ebola virus seen under a microscope. Studio_3321 / iStock / Getty Images Plus
The U.S. Food and Drug Administration (FDA) announced Thursday that it has approved a vaccine for Ebola manufactured by Merck, according to Reuters.
Merck's vaccine, Ervebo, was also approved by the European Commission in November, as STAT reported.
The vaccine was used widely by the World Health Organization and the Democratic Republic of Congo to help reduce the spread of the Ebola virus in a few West African countries from 2014 to 2016, according to Reuters. Ebola Zaire is the strain of the virus responsible for the ongoing outbreak in the Democratic Republic of the Congo, according to STAT.
The Ebola virus is extremely rare in the U.S. The only cases that have ever existed are from people infected in other countries who traveled to the U.S. or from healthcare workers who treated people infected with the virus, according to ABC News.
"Ebola virus disease is a rare but severe and often deadly disease that knows no borders," said Peter Marks, director of the FDA's Center for Biologics Evaluation and Research, in a statement reported by STAT. "Vaccination is essential to help prevent outbreaks and to stop the Ebola virus from spreading when outbreaks do occur."
Secretary of Health and Human Services Alex Azar touted the vaccine, which is a single-dose injection that works within 10 days of injection, as "a triumph of American global health leadership," according to CNN.
The Ebola Zaire virus has claimed thousands of life in West Africa and set off widespread panic during an outbreak in 2014. The current outbreak has claimed 2,000 lives in the Democratic Republic of Congo, while the outbreak in 2014 led to more than 11,000 deaths in West Africa, according to CNN.
The Ebola virus causes hemorrhagic fever, which can quickly shut down bodily functions. It spreads when a person makes direct contact with the bodily fluids of an infected person, as ABC News reported.
The vaccine is approved for patients 18 and older. It will make up a large portion of the vaccine stockpile held by the Gavi, the Vaccine Alliance, to have readily available at the next sign of an outbreak, according to STAT. Gavi recently said it planned to stockpile half a million doses of the vaccine. Ervebo is attractive to Gavi for its simplicity since it is just a single-dose and has a fairly quick immune response time of just 10 days, as STAT reported.
"While the risk of Ebola virus disease in the U.S. remains low, the U.S. government remains deeply committed to fighting devastating Ebola outbreaks in Africa, including the current outbreak in the Democratic Republic of the Congo," said Anna Abram, FDA deputy commissioner for policy, legislation and international affairs, in a statement Thursday, as ABC News reported. "Today's approval is an important step in our continuing efforts to fight Ebola in close coordination with our partners across the U.S. Department of Health and Human Services, as well as our international partners, such as the World Health Organization."
The vaccine has been in the works for decades, starting in the 90s. However, the dearth of commercial interest in an Ebola vaccine kept large pharmaceutical companies from partnering in the research and development of the drug. The outbreak in 2014 triggered a change in attitude and the drug was rapidly developed.
It underwent extensive testing, culminating in a clinical trail in Guinea, which was effected by the outbreak. Ervebo proved effective in stopping the spread of the virus, as STAT reported.More than 258,000 people have been vaccinated in the current outbreak, according to STAT.
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By Jason Farley
COVID-19 has disrupted our daily lives, and it is poised to completely disrupt the holiday season. As people make holiday plans and think about ways to reduce the risks to their loved ones, a strategy is essential.
Are masks really necessary at family gatherings?<p>If you're gathering with friends and family who don't live in your home, yes. Just because you're with people you know doesn't mean you're safe from the coronavirus. Infection rates are <a href="https://coronavirus.jhu.edu/data/new-cases-50-states" target="_blank" rel="noopener noreferrer">higher now than they have ever been</a> in the U.S., and <a href="https://youtu.be/ehdgceGzQxs" target="_blank" rel="noopener noreferrer">small gatherings have been a source</a> of viral spread. All it takes is one infected person who doesn't know they have the coronavirus to infect others.</p><p>Remember, people can be <a href="https://medical.mit.edu/covid-19-updates/2020/07/how-long-symptom-onset-person-contagious" target="_blank" rel="noopener noreferrer">contagious two to three days</a> before symptoms show – that's one thing that makes this virus so hard to stop. And it's why, even if you feel fine, you should wear a mask.</p><p>The Centers for Disease Control and Prevention now estimates that when both people are wearing masks, the <a href="https://www.cdc.gov/coronavirus/2019-ncov/more/masking-science-sars-cov2.html" target="_blank">likelihood of infection is low</a>.</p>
Who am I protecting when I wear a mask?<p>In a word: everyone. The coronavirus <a href="https://theconversation.com/aerosols-are-a-bigger-coronavirus-threat-than-who-guidelines-suggest-heres-what-you-need-to-know-142233" target="_blank">spreads through respiratory droplets</a> that you send out into the air when you talk, sing or even just breathe. The tiniest of these droplets can float on air currents for long periods.</p><p>Face masks stop many of those droplets, reducing the amount of virus in the air. That lowers your chances of getting infected, and it also lowers the chances that you'll infect someone else.</p><p><a href="https://www.cdc.gov/coronavirus/2019-ncov/more/masking-science-sars-cov2.html" target="_blank">Studies of people who had prolonged exposure</a> to others with COVID-19 have demonstrated how masks can reduce the chance of the virus spreading. In general, <a href="https://www.cdc.gov/coronavirus/2019-ncov/more/masking-science-sars-cov2.html" target="_blank" rel="noopener noreferrer">well-fitted cloth masks</a> made up of multiple layers can stop most large droplets and at least half of the tiny ones. Plastic <a href="https://doi.org/10.1101/2020.10.05.20207241" target="_blank" rel="noopener noreferrer">face shields</a> alone are far less effective. <a href="https://www.washingtonpost.com/health/2020/08/13/cdc-mask-guidance-masks-valves/" target="_blank" rel="noopener noreferrer">Face masks with valves or vents</a> might be good for construction work, but they don't stop the wearer from breathing out virus into the air.</p>
Can I reuse a mask and when should I replace it?<p>Reusable masks should be kept clean and dry. We're moving into cold and flu season, and noses get drippy. A rule of thumb: Anytime a mask is wet to the point that you can discern the wetness, it's time for a new one if it's disposable, or it's time to clean your reusable mask.</p><p>Wetness allows viruses to more easily move through paper or fabric because it allows the threads to move and may reduce the electrostatic charge in the masks that add extra protection with some fabrics.</p><p>In general, you can use a mask that stays clean and dry for about a week before you need to wash or discard it.</p>
How should I clean a cloth mask?<p>Washing your mask is like washing your clothes. You know when it is time.</p><p>In general, <a href="https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/how-to-wash-cloth-face-coverings.html" target="_blank">cleaning your mask weekly</a> should be sufficient. If odors develop before then, it's a good idea to wash it sooner. Odor generally means bacterial buildup.</p><p>Cleaning your mask by hand with soap and water is your best option. Using a general detergent on a gentle cycle in the washing machine is also fine, but that may increase the risk of damage, depending on the quality of the material. COVID-19 is not a hardy virus. Any soap or detergent should work fine. There's no need for special chemicals, bleach or harsh soaps.</p><p>Be careful to remove any inserts before washing. Inserted filters are generally not washable.</p><p>Air drying masks works best. Remember, masks should be completely dry before use. So be sure to have a replacement mask handy while the one you just washed dries.</p><p>Sunlight is always a great source of heat to dry your mask. Also, sunlight has ultraviolet radiation, which has been shown to <a href="http://doi.org/10.1111/php.13293" target="_blank" rel="noopener noreferrer">eliminate coronavirus</a> and is also known to have antibacterial properties.</p>
Can I wear the mask below my nose?<p>Wearing your mask below your nose is, frankly, ridiculous.</p><p>Think about it. If you are breathing through your nose and only covering your mouth, you are effectively eliminating the point of the mask. Properly wearing a mask requires covering both your nose and mouth at all times.</p><p>Studies show that wearing a proper cloth mask or surgical mask while exercising <a href="http://doi.org/10.1513/AnnalsATS.202008-990CME" target="_blank">doesn't affect the flow of oxygen</a> or carbon dioxide in any detectable way. So, unless you have serious heart and lung problems, that isn't an excuse.</p>
How do I safely remove my mask if I’m going to eat or drink?<p>When you <a href="https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/how-to-wash-cloth-face-coverings.html" target="_blank">take your mask off</a>, remove it carefully by the straps without touching anything else and put it somewhere safe, like wrapped in paper in a purse, bag or pocket. Then wash your hands or use hand sanitizer. When you put it back on, wash your hands again.</p>
So, how can I have a safe holiday gathering?<p>The safest way to celebrate this year is to do so with members only within your household. The <a href="https://www.cdc.gov/coronavirus/2019-ncov/daily-life-coping/holidays.html" target="_blank" rel="noopener noreferrer">CDC is now stressing that point</a>, as well. If you do celebrate with friends and relatives from outside your household, you need an action plan to reduce the risk of exposure.</p><p>Here are five recommendations:</p><ul><li>Limit the number of people – fewer people means fewer opportunities for exposure, and you'll have more room to spread out.</li><li>Require masks when not eating or drinking.</li><li>Use physical distancing when eating. Try to seat people <a href="https://doi.org/10.1136/bmj.m3223" target="_blank" rel="noopener noreferrer">at least 6 feet apart</a>. Eat outside if you can.</li><li>Consider being tested for COVID-19 before traveling or gathering. It's not a guarantee, but it can help flag illnesses. Remember to self-isolate between the test and the event.</li><li>Be prepared to self-isolate for 14 days after traveling or participating in any event that involves people from outside your home.</li></ul><p>[<em>Research into coronavirus and other news from science</em> <a href="https://theconversation.com/us/newsletters/science-editors-picks-71/?utm_source=TCUS&utm_medium=inline-link&utm_campaign=newsletter-text&utm_content=science-corona-research" target="_blank" rel="noopener noreferrer">Subscribe to The Conversation's new science newsletter</a>.]</p><p><em>The map has been updated with New Hampshire announcing a mask mandate effective Nov. 20.</em></p><p><em>Jason Farley is a professor, infectious disease-trained epidemiologist and nurse practitioner at the Johns Hopkins University School of Nursing.<br></em></p><p><em>Disclosure statement: Jason Farley, PhD, MPH, ANP-BC, FAAN receives funding from the National Institutes of Health on the Rapid Acceleration of Diagnostics for COVID-19 and Becton Dickinson for studies on SARS-CoV-2 diagnostics.</em></p><p><em>Reposted with permission from <a href="https://theconversation.com/why-face-masks-belong-at-your-thanksgiving-gathering-7-things-you-need-to-know-about-wearing-them-150130" target="_blank">The Conversation</a>. </em></p>
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Set against rising calls for action to combat growing inequality and the climate crisis, the COVID-19 pandemic underscores the importance of the key drivers of industry and economic reform: workers, communities and the environment.
The Built Environment<p>The built environment – the physical places and structures that we inhabit – is a huge potential change agent in this regard. Buildings and construction account for massive amounts of energy usage and about 40% of global CO2 emissions, providing a clear pathway to shift current consumption and production pathways.</p><p>The construction sector accounts for around <a href="https://www.mckinsey.com/~/media/McKinsey/Industries/Capital%20Projects%20and%20Infrastructure/Our%20Insights/Reinventing%20construction%20through%20a%20productivity%20revolution/MGI-Reinventing-Construction-In-Brief.pdf" target="_blank">13% of the world's GDP </a>and<a href="https://iloblog.org/2020/05/11/the-construction-sector-can-help-lead-the-economic-recovery-heres-how/" target="_blank" rel="noopener noreferrer"> for 7.2% of the global workforce</a>. Many of the jobs linked to these sector have a negative history of labour rights, especially with respect to <a href="https://laborrights.org/issues/migrant-labor" target="_blank" rel="noopener noreferrer">migrant laborers</a>. As <a href="https://iloblog.org/2020/05/11/the-construction-sector-can-help-lead-the-economic-recovery-heres-how/" target="_blank" rel="noopener noreferrer">experts have noted</a>, the scale of the industry and its relative impacts on labour markets and the environment make it a prime agent of transformation of the broader global economy.</p><p>By prioritizing approaches that focus on decarbonization and the promotion of labor rights protections, we can create economic opportunities that promote healthy, regenerative structures. Efforts are starting to seed in this regard, with <a href="https://www.vox.com/energy-and-environment/2020/1/15/21058051/climate-change-building-materials-mass-timber-cross-laminated-clt" target="_blank" rel="noopener noreferrer">increased attention</a> being placed to mass timber and other wood products in construction, as well as the use of natural materials in buildings.</p><p>At the same time, leading human rights organizations are looking more closely at promoting <a href="https://www.ihrb.org/focus-areas/built-environment/commentary-linking-climate-human-rights-built-environment-lifecycle" target="_blank" rel="noopener noreferrer">rights-based approaches</a>.</p>
Not all industries are equal. ourworldindata.org