The best of EcoWatch, right in your inbox. Sign up for our email newsletter!
Blood Test Detects More Than 50 Types of Cancer
By Richard Connor
A blood test that screens for more than 50 types of cancer could help doctors treat patients at an earlier stage than previously possible, a new study shows. The method was used to screen for more than 50 types of cancer — including particularly deadly variants such as pancreatic, ovarian, bowel and brain.
Researchers say the method — which can spot cancerous mutations before symptoms even appear — could spot particularly dangerous tumors that would otherwise go unnoticed.
The test looks for tell-tale changes to the DNA of dead cancer cells that leak into the blood as diseased tissues break down.
In their findings, reported in the Annals of Oncology, experts said the procedure was best suited to detecting cancers at a later stage of development. However, the authors said further work could result in testing that would diagnose cancers at a far earlier stage than they would be otherwise.
The test, developed by the Dana-Faber Cancer Institute and the Mayo Clinic, looks for molecules known as methyl groups that cause mutations in otherwise healthy cells, making them cancerous. It marks a change from more traditional methods that involve the sequencing of DNA.
"Our previous work indicated that methylation-based tests outperform traditional DNA-sequencing approaches to detecting multiple forms of cancer in blood samples," said Dana-Farber's Geoffrey Oxnard, a co-author of the study.
"The results of this study suggest that such assays could be a feasible way of screening people for a wide variety of cancers."
The research involved taking samples from almost 7,000 participants. In 96% of the tests, the samples correctly identified the tissue that the cancer had come from.
"Our results show that this approach to testing cell-free DNA in blood can detect a broad range of cancer types at virtually any stage of the disease, with specificity and sensitivity approaching the level needed for population-level screening," Oxnard said. "The test can be an important part of clinical trials for early cancer detection."
However, the experts said further work was needed. At present, they said, the possibility of tests not picking up cancers at their earlier stages — providing false reassurance — was too high.
Reposted with permission from Deutsche Welle.
- 110 Million Americans May Be Drinking PFAS-Contaminated Water ... ›
- Single Dose of 'Magic Mushrooms' Provides Long-Term Anxiety ... ›
- New Blood Test Can Detect Cancer 4 Years Before Symptoms - EcoWatch ›
EcoWatch Daily Newsletter
A tornado tore through a city north of Birmingham, Alabama, Monday night, killing one person and injuring at least 30.
- Tornadoes and Climate Change: What Does the Science Say ... ›
- Tornadoes Hit Unusually Wide Swaths of U.S., Alarming Climate ... ›
- 23 Dead as Tornado Pummels Lee County, AL in Further Sign ... ›
By David Konisky
On his first day in office President Joe Biden started signing executive orders to reverse Trump administration policies. One sweeping directive calls for stronger action to protect public health and the environment and hold polluters accountable, including those who "disproportionately harm communities of color and low-income communities."
Michael S. Regan, President Biden's nominee to lead the U.S. Environmental Protection Agency, grew up near a coal-burning power plant in North Carolina and has pledged to "enact an environmental justice framework that empowers people in all communities." NCDEQ
- Report Urges Biden to Reverse Trump's Environmental Rollbacks ›
- US Environmental Protection Agency (EPA) ›
- Biden's EPA Pick Michael Regan Urged to Address Environmental ... ›
- Biden Faces Pressure to Tackle 'Unfunded' Toxic Waste Sites ... ›
By Katherine Kornei
Clear-cutting a forest is relatively easy—just pick a tree and start chopping. But there are benefits to more sophisticated forest management. One technique—which involves repeatedly harvesting smaller trees every 30 or so years but leaving an upper story of larger trees for longer periods (60, 90, or 120 years)—ensures a steady supply of both firewood and construction timber.
A Pattern in the Rings<p>The <a href="https://www.encyclopedia.com/science/dictionaries-thesauruses-pictures-and-press-releases/coppice-standards-0" target="_blank">coppice-with-standards</a> management practice produces a two-story forest, said <a href="https://www.researchgate.net/profile/Bernhard_Muigg" target="_blank">Bernhard Muigg</a>, a dendrochronologist at the University of Freiburg in Germany. "You have an upper story of single trees that are allowed to grow for several understory generations."</p><p>That arrangement imprints a characteristic tree ring pattern in a forest's upper story trees (the "standards"): thick rings indicative of heavy growth, which show up at regular intervals as the surrounding smaller trees are cut down. "The trees are growing faster," said Muigg. "You can really see it with your naked eye."</p><p>Muigg and his collaborators characterized that <a href="https://ltrr.arizona.edu/about/treerings" target="_blank">dendrochronological pattern</a> in 161 oak trees growing in central Germany, one of the few remaining sites in Europe with actively managed coppice-with-standards forests. They found up to nine cycles of heavy growth in the trees, the oldest of which was planted in 1761. The researchers then turned to a historical data set — more than 2,000 oak <a href="https://eos.org/articles/podcast-discovering-europes-history-through-its-timbers" target="_blank" rel="noopener noreferrer">timbers from buildings and archaeological sites</a> in Germany and France dating from between 300 and 2015 — to look for a similar pattern.</p>
A Gap of 500 Years<p>The team found wood with the characteristic coppice-with-standards tree ring pattern dating to as early as the 6th century. That was a surprise, Muigg and his colleagues concluded, because the first mention of this forest management practice in historical documents occurred only roughly 500 years later, in the 13th century.</p><p>It's probable that forest management practices were not well documented prior to the High Middle Ages (1000–1250), the researchers suggested. "Forests are mainly mentioned in the context of royal hunting interests or donations," said Muigg. Dendrochronological studies are particularly important because they can reveal information not captured by a sparse historical record, he added.</p><p>These results were <a href="https://www.nature.com/articles/s41598-020-78933-8" target="_blank">published in December in <em>Scientific Reports</em></a>.</p><p>"It's nice to see the longevity and the history of coppice-with-standards," said <a href="https://www.teagasc.ie/contact/staff-directory/s/ian-short/" target="_blank">Ian Short</a>, a forestry researcher at Teagasc, the Agriculture and Food Development Authority in Ireland, not involved in the research. This technique is valuable because it promotes conservation and habitat biodiversity, Short said. "In the next 10 or 20 years, I think we'll see more coppice-with-standards coming back into production."</p><p>In the future, Muigg and his collaborators hope to analyze a larger sample of historic timbers to trace how the coppice-with-standards practice spread throughout Europe. It will be interesting to understand where this technique originated and how it propagated, said Muigg, and there are plenty of old pieces of wood waiting to be analyzed. "There [are] tons of dendrochronological data."</p><p><em><a href="mailto:firstname.lastname@example.org" target="_blank" rel="noopener noreferrer">Katherine Kornei</a> is a freelance science journalist covering Earth and space science. Her bylines frequently appear in Eos, Science, and The New York Times. Katherine holds a Ph.D. in astronomy from the University of California, Los Angeles.</em></p><p><em>This story originally appeared in <a href="https://eos.org/articles/tree-rings-reveal-how-ancient-forests-were-managed" target="_blank">Eos</a></em> <em>and is republished here as part of Covering Climate Now, a global journalism collaboration strengthening coverage of the climate story.</em></p>
Earth's ice is melting 57 percent faster than in the 1990s and the world has lost more than 28 trillion tons of ice since 1994, research published Monday in The Cryosphere shows.
By Jewel Fraser
Noreen Nunez lives in a middle-class neighborhood that rises up a hillside in Trinidad's Tunapuna-Piarco region.