Autism Risk Higher Near Pesticide-Treated Fields, Study Says
The study of 970 children, born in farm-rich areas of Northern California, is part of the largest project to date that is exploring links between autism and environmental exposures.
The University of California, Davis research—which used women’s addresses to determine their proximity to insecticide-treated fields—is the third project to link prenatal insecticide exposures to autism and related disorders.
“The weight of evidence is beginning to suggest that mothers’ exposures during pregnancy may play a role in the development of autism spectrum disorders,” said Kim Harley, associate director of University of California, Berkeley's Center for Environmental Research and Children's Health. She was not involved in the new study.
One in every 68 U.S. children has been identified with an autism spectrum disorder—a group of neurodevelopmental disorders characterized by difficulties with social interactions, according to the Centers for Disease Control and Prevention.
“This study does not show that pesticides are likely to cause autism, though it suggests that exposure to farming chemicals during pregnancy is probably not a good thing,” said Dr. Bennett Leventhal, a child psychiatrist at University of California, San Francisco who studies autistic children. He did not participate in the study.
The biggest known contributor to autism risk is having a family member with it. Siblings of a child with autism are 35 times more likely to develop it than those without an autistic brother or sister, according to the National Institutes of Health.
By comparison, in the new study, children with mothers who lived less than one mile from fields treated with organophosphate pesticides during pregnancy were about 60 percent more likely to have autism than children whose mothers did not live close to treated fields. Most of the women lived in the Sacramento Valley.
When women in the second trimester lived near fields treated with chlorpyrifos – the most commonly applied organophosphate pesticide—their children were 3.3 times more likely to have autism, according to the study, published in the journal Environmental Health Perspectives.
Chlorpyrifos, once widely used to kill insects in homes and gardens, was banned for residential use in 2001 after it was linked to neurological effects in children. It is still widely used on crops, including nut trees, alfalfa, vegetables and fruits.
The study also is the first to report a link between pyrethroids and autism. Application of pyrethroids just prior to conception meant an increased risk of 82 percent, and during the third trimester, the risk was 87 percent higher.
That finding is particularly concerning because “pyrethroids were supposed to be better, safer alternatives to organophosphates,” said the study’s senior author, Irva Hertz-Picciotto, an epidemiologist who leads the UC-Davis project to investigate environmental and genetic links to autism.
Use of pyrethroids has increased in recent years, both on farms and in the home, due to bans of other insecticides. Some studies now suggest pyrethroids may carry risks for developing fetuses.
The autism risk that could be attributed to an individual pesticide is likely slight, said Alycia Halladay, senior director for environmental and clinical sciences at the nonprofit Autism Speaks. “We need to understand how multiple exposures interact with each other and with genetics to understand all that is involved in the causes of autism,” she said.
But while the risks reported in the study pale in comparison to some hereditary factors, Hertz-Picciotto said they are comparable to other risks for autism, such as advanced parental age or not taking prenatal vitamins.
“In any child who develops autism, a combination of genetic and environmental factors are at work. There’s an accumulation of insults to the system. What we’re seeing is that pesticides may be one more factor that for some kids may push them over the edge,” she said.
For the study, researchers obtained the women’s addresses and compared them to a state database that provides details about where, when and how often specific commercial pesticides were used. About one-third of the women lived within approximately one mile of pesticide-treated fields.
The researchers, however, do not know whether the women were exposed to the insecticides.
“Provided that pesticides are applied responsibly and according to federally mandated label instructions, people, including expectant mothers, should not be concerned about exposure to agricultural pesticides,” said Clare Thorpe, senior director of human health policy for CropLife America, which represents pesticide manufacturers.
More than 1.1 million tons of chlorpyrifos were applied to 22,000 California farms in 2012, down from 2 million pounds on 40,000 farms in 2005, according to the database from the state Department of Pesticide Regulation.
Most of the mothers lived near fields treated with several different pesticides over their pregnancies, so it’s difficult to tease apart the potential risk of individual chemicals, said epidemiologist Janie Shelton, the lead study author. Shelton is now a consulting scientist to the United Nations.
The study also reported an increased risk of developmental delays, but not autism, in kids whose moms lived near fields where carbamates, including methomyl and Sevin, were applied.
The researchers said that pesticides could impair brain development and signaling in a way that affects social interactions, learning and behavior.
Previous studies have also linked pesticide use in California to autism spectrum disorders. In 2007, Harley and colleagues found a two-fold increase in pervasive developmental disorders (the larger group to which autism belongs) among 531 children in California’s Salinas Valley whose mothers’ urine had higher levels of organophosphate pesticides. Another study from 2007 found that mothers who lived near fields with the highest applications of two now-banned pesticides—endosulfan and dicofol—were six times more likely to have kids with autism spectrum disorders.
In recent years, rates of autism have been on the rise in the U.S. Between 2012 and 2014 alone, rates jumped 30 percent. The increase has largely been attributed to changes in diagnostic criteria for autism.
“Many children that we used to call intellectually disabled and many more with social deficits are now recognized as being on the autism spectrum,” said Kathy Katz, a pediatric psychologist at Georgetown University Medical Center in Washington, DC.
But some experts suggest that environmental exposures may also be contributing to the climbing rates. In California alone, autism diagnoses were up 600 percent between 1990 and 2001. Yet researchers found that only about one-third of the rise could be explained by changing diagnoses or kids being diagnosed at increasingly younger ages.
Earlier this year, scientists examining more than two million births in Sweden reported that inherited genes make up about 50 percent of a child’s autism risk, while environmental factors make up the other half.
It’s tempting to tie the increase in prevalence to environmental factors, said Halladay, but it’s hard to know for sure what’s going on, since some environmental risks have increased over the past few decades while others have decreased.
“Use of pesticides has gone up, so has autism. But air quality has also improved, and we know that air pollution plays a role in autism spectrum disorder risk,” she said.
Some studies are starting to look how environmental exposures may act differently in people whose genetics make them more susceptible. Earlier this year, researchers showed that people with a gene variant associated with autism and high exposure to air pollution had an increased risk of autism over people with the same gene variant but lower exposure to air pollution.
Next, Shelton hopes to look for autism risk from pesticide exposure among mothers with certain genetic variations.
“We need to know if some moms are at higher risk than others and what that risk is. Knowing who is most vulnerable is key to understanding how to better protect them,” she said.
A new report shows the U.S. government bought more than $350 million in bonds issued by oil and gas companies and induced investors to loan the industry tens of billions more at artificially low rates since the coronavirus pandemic began, Bloomberg reported.
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By Karen Charman
When President Donald Trump visited California on September 14 and dismissed the state Secretary of Natural Resources Wade Crowfoot's plea to recognize the role of climate change in the midst of the Golden State's worst and most dangerous recorded fire season to date, he gaslighted the tens of millions of West Coast residents suffering through the ordeal.
Foxes Guarding the Henhouse<p>Before he assumed power, Trump attacked regulations as unnecessary barriers to freedom and economic prosperity. Since taking office, he has targeted anything enacted by the administration of his predecessor, Barack Obama, and taken steps to withdraw the U.S. from the Paris agreement, the international effort to combat climate change. He has also staffed heads of key agencies with climate deniers of various stripes, forced out career public servants and created a hostile work environment for those who don't profess loyalty to his deregulatory agenda.</p><p>Like Trump himself, some of his cabinet choices displayed an audacious penchant for <a href="https://www.nytimes.com/interactive/2020/09/27/us/donald-trump-taxes.html?action=click&module=Spotlight&pgtype=Homepage" target="_blank">self-dealing</a> and abusing their positions of authority. One example is Trump's first Environmental Protection Agency (EPA) Administrator, Scott Pruitt, who aggressively worked to overturn Obama's climate regulations, spent most of his time in <a href="https://www.washingtonpost.com/national/health-science/trump-epa-head-steps-down-after-wave-of-ethics-management-scandals/2018/07/05/39f4251a-6813-11e8-bea7-c8eb28bc52b1_story.html" target="_blank" rel="noopener noreferrer">private meetings</a> with fossil fuel and chemical company executives, sidelined career EPA staff and reconfigured independent scientific advisory boards to make them more supportive of the industries EPA is charged with regulating. Dubbed "<a href="https://www.latimes.com/politics/la-na-pol-pruitt-leaves-20180705-story.html" target="_blank" rel="noopener noreferrer">one of the most scandal-plagued Cabinet officials in U.S. history</a>," Pruitt resigned in disgrace after revelations about his multiple brazen abuses, including using the agency as his personal concierge service and piggy bank.</p><p>Pruitt's deputy, Andrew Wheeler, a <a href="https://www.cbsnews.com/news/andrew-wheeler-acting-epa-administrator-former-number-two-before-scott-pruitt-resignation/" target="_blank">former coal industry lobbyist</a> and longtime Republican Washington insider, took over and has continued Trump's deregulatory agenda apace.</p><p>At the Department of Interior (DOI), a sprawling agency that oversees 75 percent of the country's public federal lands and includes the U.S. Geological Survey, which is tasked with evaluating natural hazards that threaten life and the health of our ecosystems, Trump installed another flamboyant anti-environmentalist to head the agency. Like Pruitt, Trump's first Interior Secretary Ryan Zinke aggressively attacked environmental regulations, <a href="https://www.washingtonpost.com/news/energy-environment/wp/2017/05/07/epa-dismisses-half-of-its-scientific-advisers-on-key-board-citing-clean-break-with-obama-administration/" target="_blank">ditched more than 200 advisory panels</a>, and pushed to open up vast swaths of public land to oil and gas drilling. Described by one environmental group as "<a href="https://www.washingtonpost.com/national/health-science/interior-secretary-zinke-resigns-amid-investigations/2018/12/15/481f9104-0077-11e9-ad40-cdfd0e0dd65a_story.html" target="_blank" rel="noopener noreferrer">the most anti-conservation Interior secretary in our nation's history</a>," Zinke was forced out after numerous highly publicized conflict-of-interest scandals.</p><p>The DOI is now run by Zinke's deputy secretary, David Bernhardt, another longtime Republican Washington insider and former oil industry lobbyist who has also been the subject of <a href="https://slate.com/news-and-politics/2020/05/this-is-still-happening-david-bernhardt-trump-lincoln.html" target="_blank">several government ethics complaints</a> for various violations favoring polluting industries.</p><p>More recently, longtime climate change denier David Legates, a climatologist at the University of Delaware previously <a href="https://insideclimatenews.org/news/19032015/u-delaware-refuses-disclose-funding-sources-its-climate-contrarian" target="_blank">funded by fossil fuel interests</a>, was hired for a <a href="https://www.npr.org/2020/09/12/912301325/longtime-climate-science-denier-hired-at-noaa" target="_blank" rel="noopener noreferrer">top job</a> advancing weather modeling and prediction at the National Oceanic and Atmospheric Administration (NOAA). Legates has called for <a href="https://www.democracynow.org/2020/9/18/noaa_david_legates_climate_crisis" target="_blank" rel="noopener noreferrer">increasing carbon emissions</a>.</p><p>The Trump administration has done much more than stack government agencies with fossil fuel industry proponents. It has removed or diluted discussion of climate change from as many government platforms as it can and decimated independent scientific advisory boards that provide unbiased, fact-based information the government needs to enact policies that protect the public. It has also <a href="https://thehill.com/policy/energy-environment/482352-trump-budget-slashes-funding-for-epa-environmental-programs" target="_blank" rel="noopener noreferrer">slashed environmental agency staffing and budgets</a>.</p>
The Damage So Far<p>A September 17 <a href="https://rhg.com/research/the-rollback-of-us-climate-policy/" target="_blank">report</a> by the Rhodium Group calculates that 1.8 billion tons more greenhouse gases will be released over the next 15 years as a result of climate change rollbacks the Trump administration has achieved so far. These include repealing Obama's main climate policy, the Clean Power Plan, which was intended to reduce dirty emissions from power plants; increasing pollution from cars by rolling back fuel economy standards and challenging California's longtime authority to set stricter emissions standards; targeting controls on hydrofluorocarbons, powerful greenhouse gases used mainly in refrigerators and air conditioners that also destroy the Earth's protective ozone layer; and allowing unreported and unregulated emissions of methane, another potent greenhouse gas, by oil and gas companies.</p><p>Besides these measures, Trump is also trying to gut core environmental statutes like the Clean Air Act, the Clean Water Act, the National Environmental Policy Act and the Endangered Species Act, all of which were enacted to protect human health and preserve a livable world.</p><p>The Paris agreement aims to keep the rise in average global temperatures at less than 2 degrees Celsius above pre-industrial levels and hopefully cap it at 1.5 degrees C or lower. We are now at approximately 1.2 degrees C and counting.</p>
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By Jan Ellen Spiegel
It wasn't so long ago that the issue of climate change was poised to play a huge – possibly even a decisive – role in the 2020 election, especially in the race for control of the U.S. Senate. Many people supporting Democratic candidates saw a possible Democratic majority as a hedge against a potential Trump re-election … a way to plug the firehose spray of more than 100 environmental regulation rollbacks and new anti-climate initiatives by the administration over its first term.
Potential Climate Voters<p>In a September 1 memo on climate and the election, Andrew Baumann, vice president of the consultants Global Strategy Group, wrote: "Few issues have seen as dramatic a shift in public opinion as climate change has over the last few years. Only marriage equality and the recent shift in views around racial justice outpace the rapid growth in the salience of climate change as an issue."</p><p>Calling it a "winning political issue" the memo says: "First, it is clearly a motivator for both younger and Latinx voters. Second, it has the power to move swing voters, particularly center-right white women."</p><p>Baumann points to a finding that when a group of such women were asked generic ballot questions, Democrats trailed by nine percentage points. But when the question was revised as a choice between:</p><p>"A Democrat who supports taking strong government action to combat climate change.<br>A Republican who opposes taking strong government action to combat climate change."</p><p>… the result was a 29 percentage point shift, putting Democrats ahead by 20 percentage points among that same group.</p><p>"I think it is playing a role," says Senator Sheldon Whitehouse, D-RI, a longtime outspoken climate activist who is on the Senate Environment and Public Works Committee and also on the Senate Democrats' Special Committee on the Climate Crisis. If Democrats win back the Senate, he stands to play an even more pivotal climate role as part of the majority. He is not up for re-election this year.</p><p><span></span>"I think from the Democratic side it's playing a role in generating enthusiasm – particularly making younger voters feel that they have a real stake in this election. On the Republican side, I think things have moved enough that candidates can no longer get away with simply scoffing about climate change."</p>
Climate a Top Concern for Youths, Latinx<p>So who's still thinking climate? Mostly young voters – 18 to 25 or 29 and Latinx voters.</p><p>Climate and the environment are the top concern among young voters, just above racism and healthcare according to <a href="https://circle.tufts.edu/latest-research/poll-young-people-believe-they-can-lead-change-unprecedented-election-cycle" target="_blank" rel="noopener noreferrer">CIRCLE</a>, the Center for Information and Research on Civic Learning and Engagement at Tufts University, which focuses on the political life of young people in the U.S. For Latinx youth, it drops a bit but remains in the top three.</p><p>The issues young people care about have an impact on how they volunteer their time, says Kristian Lundberg, an associate researcher at CIRCLE. He says that's played out most notably through the Sunrise Movement, which focuses on climate change and the environment along with other key activist groups such as Black Lives Matter and March for Our Lives.</p><p>He points to polling this summer that showed that 83% of 18-to-29-year-olds felt they had the power to change things. "Young people feel much more empowerment than in 2016 and 2018," Lundberg says. "It's intentional these movements are carving out space for young people. It's an important strategy."</p><p>In positions of power in these organizations, young people have developed peer-to-peer outreach on activism. And Lundberg says young people have made the leap that connects activism to voting as a lever for change. "In the past in very close races, young people breaking heavily have provided the margin of victory," he says.</p><p>CIRCLE is highlighting 10 U.S. Senate races as ones in which young voters can be decisive. Several of them have notable climate or environmental components – most prominently the Colorado and Montana races.</p><p>The Republican incumbents in each state – Cory Gardner in Colorado and Steve Daines in Montana – are running against a popular Democratic governor – John Hickenlooper in Colorado, now out of office — and Steve Bullock, still the governor of Montana. Both governors have had to balance their state's fossil fuel economic interests with supporting climate change solutions.</p>
Tying Climate Change to the Economy<p>In August, Data for Progress, a progressive research think tank, released polling on climate change – including in the battleground Senate elections in Arizona, Iowa, Maine, and North Carolina – showing voters back a Senate candidate supporting strong climate action.</p><blockquote>Climate change as 'mobilizing issue … key persuasion issue.'<br></blockquote><p>It also showed that linking climate change to the economy may be key. That means talking about clean energy and jobs together, says Danielle Deiseroth, climate data analyst for <a href="https://circle.tufts.edu/latest-research/poll-young-people-believe-they-can-lead-change-unprecedented-election-cycle" target="_blank">Data for Progress</a>. She says that in addition to jobs, climate change issues include climate justice and economic equality – both of heightened interest because of fallout from western wildfires.</p><p>"Climate change, we've observed over the last year or so, is a key mobilizing issue and a key persuasion issue," she says. "Climate issues can only grow support for Democratic candidates.</p><p>"I think it's pretty naive to say climate is the key issue for voters. For a lot of voters it really exemplifies so many things that are wrong with the Trump presidency," Deiseroth says.</p><p>So a factor among others. Helpful, but pivotal only in narrow circumstances.</p><p>At the League of Conservations Voters, a progressive environmentalist organization putting a lot of money and effort into the 2020 races, Senior Director of Political Affairs Craig Auster says: "I'll push back that climate change doesn't matter or isn't registering."</p><p>"It's still showing up in several Senate races. It's been playing a role in almost all of them."</p><p>Candidates are still talking about it, he says, pointing to Colorado, Montana, Iowa, and other states where ads are addressing climate and environmental issues. That shows the candidates believe their opponent is vulnerable on the issue or they're strong on it, he says.</p><p>Like others, Auster calls climate a motivator.</p><p>"Climate change matters," he says. "We have proof point after proof point about what's happening, whether it's a hurricane, a superstorm, derechos in Iowa, or wildfires out west.</p><p>"Pre-COVID it was top tier for Democratic voters along with healthcare. If COVID didn't happen I think climate would be a big deal."</p>
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Two lawmakers introduced a bill Tuesday addressing previous actions the U.S. government inflicted upon Native Americans.
The bill, authored by Rep. Deb Haaland from New Mexico and Sen. Elizabeth Warren from Massachusetts, specifically addresses the "intergenerational trauma" caused by policies that tore Native American children away from their families and sent them to boarding schools to be educated in white culture, HuffPost reported.
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By Gudrun Heise
Just as scientists are scoring successes in coronavirus research, new problems are on their way. Fall is with us and winter is around the corner, so the season for colds and flu has begun — joining COVID-19.
Influenza Vaccination<p>A flu vaccination may thus be able to narrow down the diagnostic options when flu-like symptoms occur, but whether such a vaccination also has an influence on the behavior of the dangerous new virus is — like so much else — not clear. "It is conceivable that there is an indirect effect. But it is, I believe, a matter of speculation whether it has an immunological effect in the narrower sense," says Krause.</p><p>Every winter, doctors' waiting rooms are full of people who are coughing and sniffing but who mostly turn out to have only a severe respiratory infection. According to current knowledge, the virus that causes COVID-19, SARS-CoV-2, is also likely to be subject to seasonal fluctuations. </p><p>In winter, cold viruses, at least, flourish because cold and dry air offers ideal conditions for their spread. In addition, it becomes more difficult to air rooms regularly and intensively — an important further measure to counteract the coronavirus and contain to some extent the danger posed by aerosols.</p><p>According to the <a href="https://www.rki.de/DE/Home/homepage_node.html" target="_blank">Robert Koch Institute, Germany's public health agency</a>, between 5% and 20% of people in Germany become infected with flu viruses every year. These viruses are also dangerous and can be fatal. The flu vaccination must be adapted to the influenza viruses every year, because they mutate. But at least there is a vaccination.</p><p>Most experts agree that there is unlikely to be a vaccine against the coronavirus by the time the next wave of influenza comes around. And even if a vaccine were to be approved, many unknowns remain.</p>
COVID-19 and Flu Simultaneously<p>For example, there is a lack of practical experience in dealing simultaneously with SARS-CoV-2 and influenza. It is possible to speculate that having influenza could facilitate the entry of the coronavirus into the human body. "The general weakening of the immune system during an influenza infection could increase the susceptibility of a patient to a SARS-CoV-2 infection," Krause says.</p><p>However, it is uncertain how dangerous this double infection could ultimately be and what can be done about it. Krause is of the opinion that we must arm ourselves against all three diseases — colds, flu and COVID-19. If we have a cold, bed rest, hot tea and cough medicine usually help. We can get vaccinated against flu. But how do we deal with COVID-19?</p><p><span></span>Probably people can only hope that if they get the illness, they will have a mild form with as few after-effects as possible. Here, it will certainly help to stick to suggested rules on hygiene to reduce or prevent our exposure to the virus. In an interview with DW, Bonn-based virology professor Hendrik Streeck made it clear that COVID-19 usually takes a more severe course when there is a high viral load at infection.</p>
Hygiene, Hygiene, Hygiene<p>The same hygiene measures with which we are trying to get at least some kind of grip on COVID-19 also apply to influenza. The less we come into contact with viruses, the greater the chance that we will be spared an infection or that it will be mild.</p><p>These measures include general hygiene precautions such as frequent hand washing and the wearing of protective face masks. "The various hygienic measures against COVID-19 will also reduce the spread of influenza," says Krause. "Possibly, further connections of a more immunological nature will be discovered."</p><p>Let us hope that is the case, because the flu season hasn't even started.</p>
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